SCHEMBL8219059

SCHEMBL8219059

CC(=O)c1ccccc1C(=O)NN

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSD P07339 2/20 0.58
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA9 Q16790 1/20 0.53
ALDH1A1 P00352 5/20 0.52
P2RX7 Q99572 1/20 0.52
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
GAA P10253 2/20 0.48
MAPT P10636 2/20 0.48
MITF O75030 1/20 0.48
NCOA1 Q15788 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
NCOA3 Q9Y6Q9 1/20 0.48
TSHR P16473 1/20 0.46
HTT P42858 1/20 0.46
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
SMN1; SMN2 Q16637 2/20 0.43
KDM4E B2RXH2 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30046012 0.98 CTSD (0.56) CTSDCA1CA2CA9ALDH1A1
Acetic Acid SCHEMBL27741391 0.89 CTSD (0.60) CTSDCA1CA2CA9ALDH1A1
SCHEMBL30547074 0.89 CTSD (0.63) CTSDCA1CA2CA9ALDH1A1
SCHEMBL239328 0.89 CTSD (0.63) CTSDCA1CA2CA9ALDH1A1
Hydrazine SCHEMBL14300720 0.86 CTSD (0.61) CTSDCA1CA2CA9ALDH1A1
Hydroxyamine SCHEMBL14300671 0.86 CTSD (0.61) CTSDCA1CA2CA9ALDH1A1
Hydrochloric Acid SCHEMBL6692325 0.86 CTSD (0.61) CTSDCA1CA2CA9ALDH1A1
SCHEMBL11589554 0.81 ALDH1A1 (0.42) CA1CA9ALDH1A1MAPTTSHR
SCHEMBL279655 0.81 ALDH1A1 (0.53) CA1CA2CA9ALDH1A1MEN1
SCHEMBL14880241 0.80 GAA (0.59) CA1CA9ALDH1A1GAAHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8188161-B1 Anaerobic cure systems for anaerobic curable compositions, and anaerobic curable compositions containing same HENKEL CORPORATION (US) 2012-05-29 US disclosed
EP-0481562-B1 A negative type lithographic printing plate AGFA GEVAERT NV (BE) 1998-04-01 EP disclosed
EP-0496127-B1 A negative type lithographic printing plate based on silver salt diffusion transfer AGFA GEVAERT NV (BE) 1997-09-10 EP disclosed
US-5272041-A Negative type lithographic printing plate AGFA-GEVAERT, N.V. (BE) 1993-12-21 US disclosed
EP-0496127-A1 A negative type lithographic printing plate based on silver salt diffusion transfer AGFA-GEVAERT N.V. (BE) 1992-07-29 EP disclosed
EP-0481562-A1 A negative type lithographic printing plate AGFA-GEVAERT N.V. (BE) 1992-04-22 EP disclosed
US-4358528-A Formation of black-and-white silver-containing negative images by a diffusion transfer process FUJI PHOTO FILM CO., LTD. (JP) 1982-11-09 US disclosed
US-4309499-A PROCESSING WITH ONE SOLUTION CONTAINING FOGGING AGENT, FOG PROMOTER, DEVELOPER, AND SOLVENT FOR SILVER HALIDE FUJI PHOTO FILM CO., LTD. (JP) 1982-01-05 US disclosed