Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.36 |
| ▸ | QPCT | Q16769 | 1/20 | 0.36 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.36 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL821652 | 0.80 | NR1H2 (0.37) | CYP19A1CYP1A2CYP2D6ALDH1A1TSHR | |
| SCHEMBL821353 | 0.80 | PIM1 (0.36) | CYP19A1CYP1A2CYP3A4CYP2D6POLB | |
| SCHEMBL822285 | 0.80 | ALDH1A1 (0.35) | CYP19A1CYP1A2CYP2D6ALDH1A1TSHR | |
| SCHEMBL8777923 | 0.74 | TSHR (0.46) | CYP3A4ALDH1A1TSHRLMNATP53 | |
| Hydrochloric Acid SCHEMBL821912 | 0.73 | ALDH1A1 (0.37) | CYP19A1CYP1A2CYP2D6ALDH1A1TSHR | |
| SCHEMBL28093108 | 0.73 | TP53 (0.43) | CYP19A1CYP3A4MAPTALDH1A1TSHR | |
| SCHEMBL5514135 | 0.70 | TSHR (0.46) | ALDH1A1TSHRTP53TDP1NR1H2 | |
| Iodide SCHEMBL822284 | 0.69 | TSHR (0.37) | CYP3A4MAPTALDH1A1TSHRLMNA | |
| Bromide SCHEMBL821352 | 0.69 | ALDH1A1 (0.37) | CYP3A4MAPTALDH1A1TSHRLMNA | |
| Hydrochloric Acid SCHEMBL821914 | 0.69 | ALDH1A1 (0.37) | CYP3A4MAPTALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153545-B2 | Process for homo—or copolymerization of conjugated olefins | STYRON EUROPE GMBH (CH) | 2012-04-10 | — | — | US | disclosed |
| US-20110160041-A1 | PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS | STYRON EUROPE GMBH | 2011-06-30 | — | — | US | disclosed |
| US-7915194-B2 | Process for homo- or copolymerization of conjugated olefins | STYRON EUROPE GMBH (CH) | 2011-03-29 | — | — | US | disclosed |
| EP-2267046-A1 | Process for homo- or copolymerization of conjugated olefines | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-12-29 | — | — | EP | disclosed |
| US-20100248947-A1 | PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-09-30 | — | — | US | disclosed |
| US-7612009-B2 | Process for homo-or copolymerization of conjugated olefines | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-20060142145-A1 | Process for homo-or copolymerization of conjugated olefines | TRINSEO EUROPE GMBH (CH) | 2006-06-29 | — | — | US | disclosed |
| EP-1597292-A2 | PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED OLEFINES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004076504-A2 | PROCESS FOR HOMO- OR COPOLYMERIZATION OF CONJUGATED OLEFINES | DOW GLOBAL TECHNOLOGIES, INC. (US) | 2004-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160041-A1 | PROCESS FOR HOMO - OR COPOLYMERIZATION OF CONJUGATED OLEFINS | F12, ETFB, F2 | CYP19A1 2222/4885CYP1A2 2759/4885CYP3A4 2775/4885 |
| US-20060142145-A1 | Process for homo-or copolymerization of conjugated olefines | ETFB, F12, F2 | CYP19A1 2537/4885CYP1A2 2762/4885CYP3A4 2483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.