Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 3/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL8221206 | 0.98 | CHRNA7 (0.59) | CHRNA7OPRM1OPRD1OPRK1 | |
| SCHEMBL6494545 | 0.89 | CHRNA7 (0.46) | CHRNA7OPRM1OPRD1OPRK1 | |
| SCHEMBL7007153 | 0.81 | CHRNA7 (0.61) | CHRNA7 | |
| SCHEMBL22993435 | 0.81 | CHRNA7 (0.61) | CHRNA7 | |
| Iodide SCHEMBL8219528 | 0.79 | CHRNA7 (0.59) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL7015509 | 0.79 | CHRNA7 (0.59) | CHRNA7 | |
| SCHEMBL29407568 | 0.77 | CHRNA7 (0.56) | CHRNA7 | |
| SCHEMBL22993239 | 0.77 | CHRNA7 (0.56) | CHRNA7 | |
| SCHEMBL8212966 | 0.77 | TP53 (0.48) | CHRNA7 | |
| SCHEMBL7510798 | 0.76 | CHRNA7 (0.55) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000008023-A1 | CONDENSED TRICYCLIC PIPERIDINES HAVING ANTI-CONVULSANT ACTIVITY | SMITHKLINE BEECHAM PLC (GB) | 2000-02-17 | — | — | WO | disclosed |