Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7007153 | 0.95 | CHRNA7 (0.61) | CHRNA7 | |
| Iodide SCHEMBL8219528 | 0.94 | CHRNA7 (0.59) | CHRNA7 | |
| Hydrochloric Acid SCHEMBL7015509 | 0.94 | CHRNA7 (0.59) | CHRNA7 | |
| SCHEMBL7008801 | 0.89 | CHRNA7 (0.53) | CHRNA7 | |
| SCHEMBL521174 | 0.82 | CNR1 (0.48) | CHRNA7 | |
| SCHEMBL6406991 | 0.82 | MTNR1B (0.47) | CHRNA7 | |
| SCHEMBL3475010 | 0.77 | CHRNA7 (0.90) | CHRNA7 | |
| SCHEMBL14239889 | 0.77 | CHRNA7 (0.90) | CHRNA7 | |
| SCHEMBL22993435 | 0.76 | CHRNA7 (0.61) | CHRNA7 | |
| SCHEMBL8219167 | 0.76 | CHRNA7 (0.61) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861250-B1 | AMIDINE AND ISOTHIOUREA DERIVATIVES AS INHIBITORS OF NITRIC OXIDE SYNTHASE | ASTRAZENECA AB (SE) | 2002-02-13 | — | — | EP | disclosed |
| US-6140322-A | Amidine and isothiourea derivatives as inhibitors of nitric oxide synthase | ASTRA AKTIEBOLAG (SE) | 2000-10-31 | — | — | US | disclosed |