SCHEMBL8219213

SCHEMBL8219213

CCCCCCCCCCCCCCCCCCOCCC(O)c1nc(N)c2[nH]cnc2n1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 11/20 0.51
CCNB1 P14635 11/20 0.51
CCNA2 P20248 10/20 0.49
CDK2 P24941 10/20 0.49
CCNA1 P78396 10/20 0.49
PIN1 Q13526 1/20 0.44
POLA1 P09884 1/20 0.40
PDPK1 O15530 1/20 0.39
GDA Q9Y2T3 1/20 0.39
XDH P47989 4/20 0.36
NOS1 P29475 1/20 0.36
MGMT P16455 2/20 0.34
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C19 P33261 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8215839 1.00 CDK1 (0.51) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL29351420 0.90 CDK1 (0.49) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL8219211 0.82 NOS1 (0.38) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL8215833 0.82 NOS1 (0.38) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL9218297 0.78 CDK1 (0.45) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL8207461 0.78 CDK1 (0.56) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL6897929 0.76 CDK1 (0.63) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL8219220 0.75 CDK1 (0.50) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL8215844 0.75 CDK1 (0.50) CDK1CCNB1CCNA2CDK2CCNA1
SCHEMBL1146063 0.70 CDK1 (0.61) CDK1CCNB1CCNA2CDK2CCNA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000059906-A1 AMINOHETEROCYCLE-SUBSTITUTED GLYCEROLS CLARION PHARMACEUTICALS, INC. (US) 2000-10-12 WO disclosed