Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218749 | 0.91 | CA2 (0.39) | CA2CA1ALDH1A1USP2TSHR | |
| SCHEMBL80648 | 0.85 | CA2 (0.59) | CA2CA1ALDH1A1TSHRMAPK1 | |
| SCHEMBL20394130 | 0.84 | CA2 (0.35) | THRBCA2CA1ALDH1A1USP2 | |
| SCHEMBL11158627 | 0.83 | HDAC1 (0.43) | THRBCA2CA1ALDH1A1TSHR | |
| SCHEMBL8218550 | 0.80 | THRB (0.38) | THRBMAPK1HIF1AHTTKMT2A | |
| SCHEMBL20253309 | 0.79 | CA2 (0.42) | CA2CA1ALDH1A1USP2TSHR | |
| SCHEMBL6405827 | 0.79 | CA2 (0.42) | CA2CA1ALDH1A1USP2TSHR | |
| SCHEMBL13346798 | 0.79 | THRB (0.40) | THRBALDH1A1MAPK1HIF1AHTT | |
| SCHEMBL17744958 | 0.78 | THRB (0.37) | THRBCA2CA1ALDH1A1MAPK1 | |
| SCHEMBL8402398 | 0.78 | THRB (0.37) | THRBMAPK1HIF1AHTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0580308-B1 | Working fluid composition for refrigeration machine | KAO CORP (JP) | 2000-11-15 | — | — | EP | disclosed |
| US-5395544-A | Ester-containing working fluid composition for refrigerating machine | KAO CORPORATION (JP) | 1995-03-07 | — | — | US | disclosed |
| EP-0580308-A1 | Working fluid composition for refrigeration machine | KAO CORPORATION (JP) | 1994-01-26 | — | — | EP | disclosed |