Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | DDX3X | O00571 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.49 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.48 |
| ▸ | ITGAV | P06756 | 2/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3771108 | 0.88 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1MAPK1HSD17B10 | |
| SCHEMBL13058943 | 0.87 | MEN1 (0.58) | MEN1KMT2AALDH1A1MAPK1HSD17B10 | |
| SCHEMBL19004867 | 0.85 | MEN1 (0.56) | MEN1KMT2AALDH1A1MAPK1HSD17B10 | |
| SCHEMBL13002099 | 0.84 | MEN1 (0.54) | MEN1KMT2AALDH1A1MAPK1HSD17B10 | |
| SCHEMBL26299109 | 0.82 | MEN1 (0.69) | MEN1KMT2AALDH1A1DDX3XAKR1C3 | |
| SCHEMBL3759049 | 0.81 | ITGB3 (0.58) | MEN1KMT2AALDH1A1MAPK1HSD17B10 | |
| SCHEMBL8224155 | 0.80 | HPSE (0.46) | ALDH1A1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL13058857 | 0.80 | NPC1 (0.57) | MEN1KMT2AALDH1A1MAPK1HSD17B10 | |
| SCHEMBL3221507 | 0.79 | MEN1 (0.70) | MEN1KMT2AALDH1A1DDX3XAKR1C3 | |
| Hydrochloric Acid SCHEMBL5028019 | 0.78 | MEN1 (0.68) | MEN1KMT2AALDH1A1DDX3XAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013032527-A1 | LLP2A-BISPHOSPHONATE CONJUGATES FOR OSTEOPOROSIS TREATMENT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-03-07 | — | — | WO | disclosed |
| WO-2012031228-A2 | LLP2A-BISPHOSPHONATE CONJUGATES FOR OSTEOPOROSIS TREATMENT | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-03-08 | — | — | WO | disclosed |
| WO-2008031016-A2 | HETEROCYCLIC LIGANDS FOR INTEGRIN IMAGING AND THERAPY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-03-13 | — | — | WO | disclosed |