Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 16/20 | 0.46 |
| ▸ | GBA1 | P04062 | 12/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27827297 | 0.88 | GBA1 (0.43) | GBA2GBA1 | |
| Hydrochloric Acid SCHEMBL27594553 | 0.86 | GNAO1 (0.44) | GBA2GBA1 | |
| SCHEMBL28068690 | 0.86 | GBA1 (0.41) | GBA2GBA1 | |
| SCHEMBL28030708 | 0.85 | GBA2 (0.40) | GBA2GBA1MEN1KMT2A | |
| Ammonia Solution, Strong SCHEMBL28822307 | 0.83 | GBA2 (0.39) | GBA2GBA1MEN1KMT2A | |
| SCHEMBL17477707 | 0.78 | GBA1 (0.37) | GBA1 | |
| SCHEMBL6553944 | 0.76 | TAAR1 (0.44) | GBA2GBA1 | |
| SCHEMBL7525676 | 0.73 | GBA1 (0.42) | GBA1MEN1KMT2A | |
| Iodide SCHEMBL8912480 | 0.72 | GNAO1 (0.53) | MEN1THRBHTTKMT2A | |
| SCHEMBL8219579 | 0.71 | MEN1 (0.38) | GBA2GBA1MEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059906-A1 | AMINOHETEROCYCLE-SUBSTITUTED GLYCEROLS | CLARION PHARMACEUTICALS, INC. (US) | 2000-10-12 | — | — | WO | disclosed |