Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3472430 | 0.88 | KMT2A (0.60) | KMT2AMEN1MAPTMAPK1LMNA | |
| SCHEMBL31546669 | 0.72 | KMT2A (0.62) | KMT2AMEN1MAPTMAPK1LMNA | |
| SCHEMBL29708112 | 0.69 | MAPK1 (0.55) | MAPTMAPK1LMNACYP3A4L3MBTL1 | |
| SCHEMBL203086 | 0.69 | MAPK1 (0.55) | MAPTMAPK1LMNACYP3A4L3MBTL1 | |
| SCHEMBL14392423 | 0.69 | ERN1 (0.47) | KMT2AMEN1MAPTMAPK1POLB | |
| SCHEMBL3472249 | 0.69 | LMNA (0.59) | KMT2AMEN1MAPTMAPK1LMNA | |
| SCHEMBL15989344 | 0.69 | ERN1 (0.46) | MAPTCYP3A4 | |
| SCHEMBL6781658 | 0.69 | RECQL (0.46) | KMT2AMEN1MAPTMAPK1LMNA | |
| SCHEMBL19295317 | 0.68 | ALDH1A1 (0.49) | KMT2AMEN1MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL3473431 | 0.67 | LMNA (0.54) | KMT2AMEN1MAPTMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006479-A1 | 2-(HETEROARYL) ALKYL INDAZOLE 6-PHENYL AND THIENYL METHYL AMIDE AS THROMBIN INHIBITORS | BAYER HEALTHCARE AG (DE) | 2008-01-17 | — | — | WO | disclosed |