Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC15A1 | P46059 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 5/20 | 0.39 |
| ▸ | MMP1 | P03956 | 2/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219642 | 1.00 | SLC15A1 (0.42) | SLC15A1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL8220082 | 0.99 | ALDH1A1 (0.42) | SLC15A1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL8216129 | 0.99 | ALDH1A1 (0.42) | SLC15A1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL8217014 | 0.99 | ALDH1A1 (0.42) | SLC15A1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL8211421 | 0.99 | ALDH1A1 (0.42) | SLC15A1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL8220075 | 0.99 | ALDH1A1 (0.42) | SLC15A1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL8216132 | 0.99 | ALDH1A1 (0.42) | SLC15A1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL8211422 | 0.99 | ALDH1A1 (0.42) | SLC15A1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL8217015 | 0.99 | ALDH1A1 (0.42) | SLC15A1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL8209349 | 0.85 | SLC15A1 (0.43) | SLC15A1ALDH1A1MAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0621270-B1 | Piperazine derivatives as collagenase inhibitors | SANKYO CO (JP) | 2000-04-12 | — | — | EP | disclosed |
| US-5643908-A | ANGIOGENESIS INHIBITOR, ANTITUMOR | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0621270-A1 | COLLAGENASE INHIBITOR | SANKYO COMPANY LIMITED (JP) | 1994-10-26 | — | — | EP | disclosed |