Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.48 |
| ▸ | DPP8 | Q6V1X1 | 12/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 12/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.48 |
| ▸ | LTA4H | P09960 | 1/20 | 0.48 |
| ▸ | FAP | Q12884 | 9/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781929 | 1.00 | DPP4 (0.48) | DPP4DPP8DPP9DPP7LTA4H | |
| SCHEMBL8218015 | 0.82 | DPP4 (0.48) | DPP4DPP8DPP9DPP7LTA4H | |
| SCHEMBL4801659 | 0.82 | DPP4 (0.48) | DPP4DPP8DPP9DPP7LTA4H | |
| SCHEMBL8216125 | 0.81 | DPP4 (0.52) | DPP4DPP8DPP9DPP7FAP | |
| Hydrochloric Acid SCHEMBL4728792 | 0.79 | LTA4H (0.47) | DPP4DPP8DPP9DPP7LTA4H | |
| SCHEMBL4782189 | 0.77 | DPP4 (0.49) | DPP4DPP8DPP9DPP7LTA4H | |
| SCHEMBL8213925 | 0.77 | DPP4 (0.49) | DPP4DPP8DPP9DPP7LTA4H | |
| Hydrochloric Acid SCHEMBL6491094 | 0.75 | MEN1 (0.59) | LTA4HNPC1RAB9AMEN1KMT2A | |
| SCHEMBL4726747 | 0.75 | DPP4 (0.60) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL4726746 | 0.75 | DPP4 (0.60) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008029217-A2 | DIPEPTIDYL PEPTIDASE IV INHIBITORS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2008-03-13 | — | — | WO | disclosed |