Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.60 |
| ▸ | MGLL | Q99685 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | PAM | P19021 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12565648 | 1.00 | DGKA (0.60) | DGKAMGLLDNM1PAMKDM4E | |
| SCHEMBL28796910 | 1.00 | DGKA (0.60) | DGKAMGLLDNM1PAMKDM4E | |
| SCHEMBL821592 | 1.00 | DGKA (0.60) | DGKAMGLLDNM1PAMKDM4E | |
| SCHEMBL176410 | 1.00 | DGKA (0.60) | DGKAMGLLDNM1PAMKDM4E | |
| SCHEMBL8065894 | 1.00 | DGKA (0.60) | DGKAMGLLDNM1PAMKDM4E | |
| SCHEMBL821584 | 1.00 | DGKA (0.60) | DGKAMGLLDNM1PAMKDM4E | |
| SCHEMBL12565650 | 1.00 | DGKA (0.60) | DGKAMGLLDNM1PAMKDM4E | |
| SCHEMBL12565651 | 1.00 | DGKA (0.60) | DGKAMGLLDNM1PAMKDM4E | |
| SCHEMBL206255 | 0.97 | DGKA (0.56) | DGKAMGLLDNM1PAMKDM4E | |
| SCHEMBL822217 | 0.95 | DGKA (0.56) | DGKAMGLLDNM1PAMKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-11-24 | — | — | US | disclosed |
| US-20110287102-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | UMPS, PUF60, SMCHD1 | DGKA 1315/4885MGLL 1273/4885DNM1 4718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.