Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215878 | 0.87 | UCHL1 (0.49) | UCHL1NPC1HSD11B1LMNANPSR1 | |
| SCHEMBL2136252 | 0.87 | NPC1 (0.53) | UCHL1NPC1HSD11B1LMNANPSR1 | |
| SCHEMBL1795426 | 0.87 | NPC1 (0.53) | UCHL1NPC1HSD11B1LMNANPSR1 | |
| SCHEMBL1251121 | 0.87 | NPC1 (0.53) | UCHL1NPC1HSD11B1LMNANPSR1 | |
| SCHEMBL8222788 | 0.86 | USP30 (0.53) | UCHL1NPC1HSD11B1LMNANPSR1 | |
| SCHEMBL8221674 | 0.85 | NPC1 (0.55) | UCHL1NPC1HSD11B1LMNANPSR1 | |
| SCHEMBL10132254 | 0.84 | UCHL1 (0.53) | UCHL1NPC1LMNANPSR1KDM4E | |
| SCHEMBL10132357 | 0.84 | ALDH1A1 (0.56) | UCHL1NPC1LMNANPSR1KDM4E | |
| SCHEMBL3530509 | 0.83 | NPC1 (0.57) | UCHL1NPC1LMNANPSR1KDM4E | |
| SCHEMBL5408443 | 0.83 | NPC1 (0.57) | UCHL1NPC1LMNANPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008018639-A2 | GLYCINE TRANSPORTER INHIBITOR | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2008-02-14 | — | — | WO | disclosed |