SCHEMBL8219986

SCHEMBL8219986

CC(C)(C)C1=C([Si](C)(C)NC2CCCCC2)C=CC1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8217606 0.78 LMNA (0.34) LMNA
SCHEMBL8218119 0.77
SCHEMBL8220114 0.76 KDM4E (0.30)
SCHEMBL8216254 0.74
SCHEMBL8208213 0.72 CYP1A2 (0.30) CYP1A2CYP2D6CYP2C9CYP2C19
SCHEMBL8218241 0.70 LMNA (0.31) LMNA
SCHEMBL7942218 0.68
SCHEMBL8209130 0.67 NPC1 (0.35)
SCHEMBL8216325 0.66 KDM4E (0.32) CYP1A2CYP2C19
SCHEMBL8216556 0.63 KDM4E (0.34) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136995-A Process for producing aminosilane compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-24 US disclosed