SCHEMBL8209130

SCHEMBL8209130

CC(C)C1=C([Si](C)(C)NC2CCCCC2)CC=C1

nearest known ligand 0.35

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.35
TSHR P16473 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
CNR2 P34972 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8220094 0.80 L3MBTL1 (0.35) SMN1; SMN2
SCHEMBL8220114 0.80 KDM4E (0.30)
SCHEMBL8218241 0.80 LMNA (0.31)
SCHEMBL8208147 0.78 GAA (0.36) RAB9ASMN1; SMN2
SCHEMBL8207263 0.74
SCHEMBL8218119 0.74
SCHEMBL8216446 0.71
SCHEMBL25259680 0.70
SCHEMBL8215591 0.70 EPHX1 (0.37) NPC1RAB9ASMN1; SMN2CNR2
SCHEMBL10319439 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6136995-A Process for producing aminosilane compounds SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-10-24 US disclosed