Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 13/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 1.00 |
| ▸ | LMNA | P02545 | 3/20 | 1.00 |
| ▸ | TP53 | P04637 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 3/20 | 1.00 |
| ▸ | NFKB1 | P19838 | 2/20 | 1.00 |
| ▸ | CYP1A2 | P05177 | 2/20 | 1.00 |
| ▸ | STAT6 | P42226 | 2/20 | 1.00 |
| ▸ | MAPT | P10636 | 2/20 | 1.00 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 1.00 |
| ▸ | CASP1 | P29466 | 1/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 1/20 | 1.00 |
| ▸ | NFKB2 | Q00653 | 1/20 | 1.00 |
| ▸ | RELA | Q04206 | 1/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 1/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 1/20 | 1.00 |
| ▸ | THPO | P40225 | 1/20 | 1.00 |
| ▸ | HTT | P42858 | 1/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 1/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Parthenolide SCHEMBL29811034 | 1.00 | PKM (1.00) | PKMALDH1A1LMNATP53CYP3A4 | |
| Parthenolide SCHEMBL6479221 | 1.00 | PKM (1.00) | PKMALDH1A1LMNATP53CYP3A4 | |
| Parthenolide SCHEMBL20438846 | 1.00 | PKM (1.00) | PKMALDH1A1LMNATP53CYP3A4 | |
| Parthenolide SCHEMBL1753337 | 1.00 | PKM (1.00) | PKMALDH1A1LMNATP53CYP3A4 | |
| Parthenolide SCHEMBL8219 | 1.00 | PKM (1.00) | PKMALDH1A1LMNATP53CYP3A4 | |
| Parthenolide SCHEMBL14418063 | 1.00 | PKM (1.00) | PKMALDH1A1LMNATP53CYP3A4 | |
| Parthenolide SCHEMBL14339765 | 1.00 | PKM (1.00) | PKMALDH1A1LMNATP53CYP3A4 | |
| Parthenolide SCHEMBL13367522 | 1.00 | PKM (1.00) | PKMALDH1A1LMNATP53CYP3A4 | |
| Parthenolide SCHEMBL21998728 | 1.00 | PKM (1.00) | PKMALDH1A1LMNATP53CYP3A4 | |
| Parthenolide SCHEMBL30383005 | 1.00 | PKM (1.00) | PKMALDH1A1LMNATP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 5695 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260124203-A1 | CHEMICAL SYNTHETIC LETHALITY FOR ANTIMICROBIAL THERAPY | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2026-05-07 | — | — | US | claimed |
| US-20260125650-A1 | METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES | TRAILHEAD BIOSYSTEMS INC (US) | 2026-05-07 | — | — | US | claimed |
| US-12618044-B2 | Specification of functional cranial placode derivatives from human pluripotent stem cells | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2026-05-05 | — | — | US | claimed |
| EP-4724079-A2 | METHODS AND COMPOSITIONS FOR THE TREATMENT OF AGE-RELATED MACULAR DEGENERATION | Stealth BioTherapeutics Inc. (US) | 2026-04-15 | — | — | EP | claimed |
| EP-4719404-A2 | METHODS FOR ADDRESSING INJECTION SITE REACTIONS ASSOCIATED WITH THE ADMINISTRATION OF BEVEMIPRETIDE | Stealth BioTherapeutics Inc. (US) | 2026-04-08 | — | — | EP | claimed |
| US-20260091162-A1 | SPRAYABLE POLYMERIC SCAFFOLD LOADED WITH INFLAMMASOME-INHIBITING LIPID NANORODS FOR ANTI-INFLAMMATION THERAPY | KULKARNI ASHISH (US) | 2026-04-02 | — | — | US | claimed |
| EP-4714440-A2 | A HEALING HERBAL-MINERAL COMPOSITION WITH ENHANCED EFFECTS | Kurek, Janusz (PL) | 2026-03-25 | — | — | EP | claimed |
| US-12569494-B2 | Compositions and methods to promote thymic regeneration | FRED HUTCHINSON CANCER CENTER (US) | 2026-03-10 | — | — | US | claimed |
| US-20260048096-A1 | METHODS AND COMPOSITIONS FOR PRESERVING THE RETINAL OUTER NUCLEAR LAYER (ONL), PHOTORECEPTORS, AND RETINAL THICKNESS | STEALTH BIOTHERAPEUTICS INC. (US) | 2026-02-19 | — | — | US | claimed |
| EP-4661876-A1 | METABOLIC INHIBITORS AND METHODS OF MAKING AND USING THEREOF | University of Miami (US) | 2025-12-17 | — | — | EP | claimed |
| US-5466451-A | Carbon dioxide, supercritical | SCHAPER & BRUEMMER GMBH & CO., KG (DE) | 1995-11-14 | — | — | US | claimed |
| US-5384121-A | Method for the extraction of sesquiterpene lactones | RHODES TECHNOLOGY (GB) | 1995-01-24 | — | — | US | claimed |
| EP-0614459-A1 | METHOD FOR OBTAINING SESQUITERPENE LACTONE, IN PARTICULAR PARTHENOLIDE | MADECA (FR) | 1994-09-14 | — | — | EP | claimed |
| WO-1994006800-A1 | METHOD FOR OBTAINING SESQUITERPENE LACTONE, IN PARTICULAR PARTHENOLIDE | MADECA (FR) | 1994-03-31 | — | — | WO | claimed |
| EP-0565578-A1 | METHOD FOR THE EXTRACTION OF SESQUITERPENE LACTONES | RHODES TECHNOLOGY LTD. (GB) | 1993-10-20 | — | — | EP | claimed |
| CN-1074615-A | The effective medicinal components of Flos Pyrethri parthenii, its extracting process and contain the medicament of this effective medicinal components | SCHAPER & BRUEMMER GMBH (DE) | 1993-07-28 | — | — | CN | claimed |
| WO-1992011857-A1 | METHOD FOR THE EXTRACTION OF SESQUITERPENE LACTONES | RHODES TECHNOLOGY LTD. (GB) | 1992-07-23 | — | — | WO | claimed |
| EP-0098041-B1 | SESQUITERPENE LACTONES, EXTRACTS CONTAINING THEM, THEIR PREPARATION AND PHARMACEUTICAL USE | R.P. SCHERER CORPORATION (US) | 1989-08-02 | — | — | EP | claimed |
| US-4758433-A | Oil extract of Tanacetum parthenium for treating migraine | R. P. SCHERER CORP. (US) | 1988-07-19 | — | — | US | claimed |
| EP-0098041-A2 | Sesquiterpene lactones, extracts containing them, their preparation and pharmaceutical use | R.P. SCHERER CORPORATION (US) | 1984-01-11 | — | — | EP | claimed |