Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.32 |
| ▸ | PYGM | P11217 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4878389 | 0.74 | SLC22A12 (0.43) | SLC22A12NPC1RAB9A | |
| SCHEMBL4858244 | 0.66 | SLC22A12 (0.41) | SLC22A12NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4858249 | 0.66 | SLC22A12 (0.41) | SLC22A12NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28441844 | 0.66 | SLC22A12 (0.53) | SLC22A12NPC1RAB9A | |
| SCHEMBL4809049 | 0.65 | ALOX15 (0.52) | SLC22A12NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4872929 | 0.64 | DCTPP1 (0.35) | NPC1RAB9A | |
| SCHEMBL4873110 | 0.62 | SLC22A12 (0.41) | SLC22A12 | |
| SCHEMBL4873114 | 0.62 | SLC22A12 (0.41) | SLC22A12 | |
| SCHEMBL14194769 | 0.61 | MAPK14 (0.42) | SMN1; SMN2 | |
| SCHEMBL4876533 | 0.61 | MAPT (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008004117-A1 | SELECTIVE AZOLE PDE10A INHIBITOR COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2008-01-10 | — | — | WO | disclosed |