Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | PKLR | P30613 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12656054 | 0.85 | KMT2A (0.63) | GAAL3MBTL1PKMPKLRCYP3A4 | |
| SCHEMBL13271173 | 0.83 | USP2 (0.62) | GAAL3MBTL1PKMPKLREPHX2 | |
| SCHEMBL8220526 | 0.82 | AKR1C3 (0.50) | PKMPKLRKMT2AMEN1ALDH1A1 | |
| SCHEMBL3633792 | 0.81 | USP2 (0.71) | GAAL3MBTL1PKMPKLREPHX2 | |
| SCHEMBL15231766 | 0.80 | MAPT (0.65) | GAAL3MBTL1PKMPKLRCYP3A4 | |
| SCHEMBL2299332 | 0.79 | KMT2A (0.51) | GAAL3MBTL1PKMPKLRCYP3A4 | |
| SCHEMBL5338240 | 0.79 | POLB (0.67) | GAAL3MBTL1PKMPKLRKMT2A | |
| SCHEMBL16627264 | 0.79 | ATM (0.63) | GAAL3MBTL1PKMPKLRUSP2 | |
| Hydrochloric Acid SCHEMBL3246796 | 0.79 | MAPT (0.63) | GAAL3MBTL1PKMPKLRCYP3A4 | |
| SCHEMBL13548367 | 0.78 | PKM (0.66) | GAAPKMHSD11B1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |