Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.50 |
| ▸ | CTSG | P08311 | 1/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3629308 | 0.85 | ALDH1A1 (0.63) | CTSGCMA1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL3629646 | 0.84 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL10250933 | 0.82 | PKM (0.56) | AKR1C3AKR1C1CTSGCMA1SCN9A | |
| SCHEMBL20183354 | 0.82 | CTSG (0.49) | AKR1C3AKR1C1CTSGCMA1SCN9A | |
| SCHEMBL8220120 | 0.82 | GAA (0.56) | ALDH1A1SMN1; SMN2GBA1PKMPKLR | |
| SCHEMBL24317428 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2PKMPKLRMEN1 | |
| SCHEMBL29532805 | 0.81 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2PKMPKLRMEN1 | |
| SCHEMBL24571620 | 0.79 | JAK2 (0.51) | CTSGCMA1SCN9AALDH1A1SMN1; SMN2 | |
| SCHEMBL15014519 | 0.79 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2961172 | 0.78 | HTT (0.61) | CTSGCMA1ALDH1A1SMN1; SMN2GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |