Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 6/20 | 0.36 |
| ▸ | FNTB | P49356 | 5/20 | 0.36 |
| ▸ | FNTA | P49354 | 4/20 | 0.36 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GPR6 | P46095 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4380271 | 0.83 | MEN1 (0.42) | ABL1CCR5GPR6 | |
| SCHEMBL4388230 | 0.70 | MEN1 (0.46) | SMN1; SMN2MAOBGPR6 | |
| SCHEMBL4383840 | 0.69 | MEN1 (0.46) | SMN1; SMN2GPR6 | |
| SCHEMBL22035962 | 0.67 | ALDH1A1 (0.55) | CYP2C19SMN1; SMN2 | |
| SCHEMBL4383832 | 0.66 | MEN1 (0.43) | CYP2C19SMN1; SMN2GPR6 | |
| SCHEMBL8219942 | 0.65 | ALDH1A1 (0.37) | — | |
| SCHEMBL4380261 | 0.65 | MEN1 (0.42) | GPR6 | |
| SCHEMBL4385346 | 0.64 | MEN1 (0.43) | CYP2C19SMN1; SMN2GPR6 | |
| SCHEMBL14774922 | 0.63 | EPHX2 (0.47) | — | |
| SCHEMBL8225083 | 0.61 | MET (0.46) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |