Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | CNR2 | P34972 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.44 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9493283 | 1.00 | NR5A1 (0.51) | NR5A1TSHRTP53PLA2G4BLTA4H | |
| SCHEMBL30620165 | 1.00 | NR5A1 (0.51) | NR5A1TSHRTP53PLA2G4BLTA4H | |
| SCHEMBL8209170 | 1.00 | NR5A1 (0.51) | NR5A1TSHRTP53PLA2G4BLTA4H | |
| SCHEMBL6656507 | 1.00 | NR5A1 (0.51) | NR5A1TSHRTP53PLA2G4BLTA4H | |
| SCHEMBL29955228 | 0.98 | NR5A1 (0.49) | NR5A1TSHRTP53PLA2G4BLTA4H | |
| SCHEMBL6556182 | 0.98 | NR5A1 (0.49) | NR5A1TSHRTP53PLA2G4BLTA4H | |
| SCHEMBL29955018 | 0.95 | LTA4H (0.43) | NR5A1LTA4HPDK2 | |
| SCHEMBL8405356 | 0.95 | LTA4H (0.43) | NR5A1LTA4HPDK2 | |
| SCHEMBL29953890 | 0.89 | LTA4H (0.43) | LTA4HPDK2 | |
| SCHEMBL6676037 | 0.88 | RARB (0.53) | NR5A1TSHRTP53PLA2G4BLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0767772-B1 | NOVEL CHIRAL CYCLOHEXYL COMPOUNDS | SECR DEFENCE (GB) | 2000-08-30 | — | — | EP | disclosed |
| US-5853613-A | Chiral cyclohexyl compounds | SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1998-12-29 | — | — | US | disclosed |
| EP-0767772-A1 | NOVEL CHIRAL CYCLOHEXYL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1997-04-16 | — | — | EP | disclosed |
| WO-1996000710-A1 | NOVEL CHIRAL CYCLOHEXYL COMPOUNDS | THE SECRETARY OF STATE FOR DEFENCE (GB) | 1996-01-11 | — | — | WO | disclosed |