Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.43 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955018 | 1.00 | LTA4H (0.43) | LTA4HNR5A1MCL1MEN1NPC1 | |
| SCHEMBL29955228 | 0.97 | NR5A1 (0.49) | LTA4HNR5A1PDK2 | |
| SCHEMBL6556182 | 0.97 | NR5A1 (0.49) | LTA4HNR5A1PDK2 | |
| SCHEMBL8220604 | 0.95 | NR5A1 (0.51) | LTA4HNR5A1PDK2 | |
| SCHEMBL30620165 | 0.95 | NR5A1 (0.51) | LTA4HNR5A1PDK2 | |
| SCHEMBL9493283 | 0.95 | NR5A1 (0.51) | LTA4HNR5A1PDK2 | |
| SCHEMBL8209170 | 0.95 | NR5A1 (0.51) | LTA4HNR5A1PDK2 | |
| SCHEMBL6656507 | 0.95 | NR5A1 (0.51) | LTA4HNR5A1PDK2 | |
| SCHEMBL29953890 | 0.93 | LTA4H (0.43) | LTA4HMEN1NPC1MAPTRAB9A | |
| SCHEMBL16265305 | 0.87 | RARB (0.56) | LTA4HNR5A1MCL1RARARARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10202508-B2 | Dye compounds | MERCK PATENT GMBH (DE) | 2019-02-12 | — | — | US | disclosed |
| US-9879183-B2 | Liquid crystal compound having CF2O bonding group and tolan skeleton, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2018-01-30 | — | — | US | disclosed |
| US-20170273955-A1 | AZAINDOLE DERIVATIVE HAVING AMPK-ACTIVATING ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2017-09-28 | — | — | US | disclosed |
| US-20170107427-A1 | LIQUID CRYSTAL COMPOUND HAVING CF2O BONDING GROUP AND TOLAN SKELETON, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170107427-A1 | LIQUID CRYSTAL COMPOUND HAVING CF2O BONDING GROUP AND TOLAN SKELETON, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORPORATION (JP) | 2017-04-20 | — | — | US | disclosed |
| US-20170002203-A1 | DYE COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-01-05 | — | — | US | disclosed |
| US-20170002203-A1 | DYE COMPOUNDS | MERCK PATENT GMBH (DE) | 2017-01-05 | — | — | US | disclosed |
| WO-2016031842-A1 | AZAINDOLE DERIVATIVE HAVING AMPK-ACTIVATING EFFECT | 塩野義製薬株式会社 | 2016-03-03 | — | — | WO | disclosed |
| US-7910018-B2 | Compounds for use in liquid crystal devices | QINETIQ LIMITED (GB) | 2011-03-22 | — | — | US | disclosed |
| US-20090066905-A1 | Componds for use in liquid crystal devices | QINETIQ LIMITED (GB) | 2009-03-12 | — | — | US | disclosed |
| US-20040229911-A1 | New pharmaceutical combinations for NOS inhibitors | PFIZER INC | 2004-11-18 | — | — | US | disclosed |
| EP-0453503-B1 | PHENYL NAPHTHALENES HAVING LIQUID CRYSTALLINE PROPERTIES | SECR DEFENCE BRIT (GB) | 1995-03-22 | — | — | EP | disclosed |
| US-5252253-A | Phenyl naphthalenes having liquid crystalline properties | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1993-10-12 | — | — | US | disclosed |
| EP-0453503-A1 | PHENYL NAPHTHALENES HAVING LIQUID CRYSTALLINE PROPERTIES. | SECR DEFENCE BRIT (GB) | 1991-10-30 | — | — | EP | disclosed |
| WO-1990008119-A1 | PHENYL NAPHTHALENES HAVING LIQUID CRYSTALLINE PROPERTIES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNIC MAJESTY'S GOVERNMENT OF THE UNITED KINGDOM OF GREAT BRITAIN AND NORTHERN IRELAND (GB) | 1990-07-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090066905-A1 | Componds for use in liquid crystal devices | FZD7, CFD, PYCARD | LTA4H 1730/4885NR5A1 148/4885MCL1 3069/4885 |
| US-20170107427-A1 | LIQUID CRYSTAL COMPOUND HAVING CF2O BONDING GROUP AND TOLAN SKELETON, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | PIEZO1, TLN1, TCOF1 | LTA4H 1298/4885NR5A1 3423/4885MCL1 2392/4885 |
| US-20170273955-A1 | AZAINDOLE DERIVATIVE HAVING AMPK-ACTIVATING ACTIVITY | PRKAA1, PRKAA2, PRKAG1 | LTA4H 3505/4885NR5A1 1501/4885MCL1 3404/4885 |
| US-20040229911-A1 | New pharmaceutical combinations for NOS inhibitors | NOS1, NOS3, NPBWR1 | LTA4H 2624/4885NR5A1 167/4885MCL1 2792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.