Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31616998 | 0.89 | TBXAS1 (0.40) | TBXAS1CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL31617023 | 0.89 | TBXAS1 (0.40) | TBXAS1CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL31616963 | 0.89 | TBXAS1 (0.40) | TBXAS1CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL31617035 | 0.87 | TBXAS1 (0.40) | TBXAS1CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL31616927 | 0.87 | TBXAS1 (0.40) | TBXAS1CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL31617070 | 0.87 | TBXAS1 (0.40) | TBXAS1CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL31616999 | 0.87 | TERT (0.41) | TBXAS1CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL1146495 | 0.86 | TBXAS1 (0.59) | TBXAS1CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL5675657 | 0.86 | TBXAS1 (0.59) | TBXAS1CYP1A2CYP3A4CYP2D6CYP19A1 | |
| SCHEMBL28776154 | 0.86 | TBXAS1 (0.59) | TBXAS1CYP1A2CYP3A4CYP2D6CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000059906-A1 | AMINOHETEROCYCLE-SUBSTITUTED GLYCEROLS | CLARION PHARMACEUTICALS, INC. (US) | 2000-10-12 | — | — | WO | disclosed |