Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.39 |
| ▸ | AQP1 | P29972 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.33 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8225826 | 1.00 | CA2 (0.50) | CA2ADRA1AADRA1DADRA1BAQP1 | |
| SCHEMBL4961501 | 1.00 | CA2 (0.50) | CA2ADRA1AADRA1DADRA1BAQP1 | |
| SCHEMBL8228420 | 0.93 | CA2 (0.46) | CA2ADRA1AADRA1DADRA1BAQP1 | |
| SCHEMBL8225729 | 0.91 | CA2 (0.46) | CA2ADRA1AADRA1DADRA1BAQP1 | |
| SCHEMBL8220833 | 0.90 | CA2 (0.44) | CA2ADRA1AADRA1DADRA1BAQP1 | |
| SCHEMBL8220394 | 0.90 | CA2 (0.44) | CA2ADRA1AADRA1DADRA1BAQP1 | |
| SCHEMBL4961674 | 0.89 | CA2 (0.50) | CA2ADRA1AADRA1DADRA1BAQP1 | |
| SCHEMBL8225803 | 0.89 | CA2 (0.50) | CA2ADRA1AADRA1DADRA1BAQP1 | |
| SCHEMBL4963694 | 0.89 | CA2 (0.50) | CA2ADRA1AADRA1DADRA1BAQP1 | |
| SCHEMBL4963942 | 0.88 | CA2 (0.49) | CA2ADRA1AADRA1DADRA1BAQP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241172-A1 | Benzodioxane and benzodioxolane derivatives and uses thereof | WYETH (US) | 2006-10-26 | — | — | US | disclosed |
| US-20060241172-A1 | Benzodioxane and benzodioxolane derivatives and uses thereof | WYETH (US) | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241172-A1 | Benzodioxane and benzodioxolane derivatives and uses thereof | HTR2C, HTR1D, HTR1A | CA2 4153/4885ADRA1A 37/4885ADRA1D 21/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.