Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 18/20 | 0.75 |
| ▸ | OXTR | P30559 | 1/20 | 0.44 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8228560 | 0.93 | THRB (0.70) | THRBOXTRJAK1 | |
| SCHEMBL8225971 | 0.86 | THRB (0.59) | THRBOXTR | |
| SCHEMBL5368006 | 0.86 | THRB (1.00) | THRB | |
| SCHEMBL8228140 | 0.85 | THRB (0.71) | THRB | |
| SCHEMBL8226026 | 0.85 | THRB (0.58) | THRBOXTR | |
| SCHEMBL8230282 | 0.84 | THRB (0.75) | THRB | |
| SCHEMBL8229477 | 0.84 | THRB (0.71) | THRB | |
| SCHEMBL8228464 | 0.82 | THRB (0.71) | THRBOXTR | |
| SCHEMBL8219764 | 0.82 | THRB (0.75) | THRB | |
| SCHEMBL8229487 | 0.82 | THRB (0.68) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |