Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | OXTR | P30559 | 8/20 | 0.47 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.46 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8226026 | 0.90 | THRB (0.58) | THRBOXTRAVPR1AMEN1KMT2A | |
| SCHEMBL8228560 | 0.87 | THRB (0.70) | THRBOXTRAVPR1A | |
| SCHEMBL8220883 | 0.86 | THRB (0.75) | THRBOXTR | |
| SCHEMBL8229481 | 0.81 | THRB (0.55) | THRBOXTR | |
| SCHEMBL8228464 | 0.80 | THRB (0.71) | THRBOXTR | |
| SCHEMBL8225249 | 0.79 | THRB (0.57) | THRB | |
| SCHEMBL8228559 | 0.78 | THRB (0.56) | THRB | |
| SCHEMBL8228557 | 0.77 | THRB (0.58) | THRB | |
| SCHEMBL8225964 | 0.77 | THRB (0.58) | THRB | |
| SCHEMBL8228162 | 0.77 | THRB (0.57) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007140982-A1 | SUBSTITUTED BENZOXAZOLES | BAYER HEALTHCARE AG (DE) | 2007-12-13 | — | — | WO | disclosed |