Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.85 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.85 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.85 |
| ▸ | MEN1 | O00255 | 6/20 | 0.85 |
| ▸ | TP53 | P04637 | 4/20 | 0.85 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.85 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.85 |
| ▸ | LMNA | P02545 | 7/20 | 0.80 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.80 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.79 |
| ▸ | RECQL | P46063 | 1/20 | 0.79 |
| ▸ | ESR1 | P03372 | 5/20 | 0.79 |
| ▸ | PGR | P06401 | 2/20 | 0.79 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.79 |
| ▸ | AR | P10275 | 2/20 | 0.79 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.79 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.79 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19286812 | 1.00 | MAPT (0.85) | MAPTKMT2ACYP3A4MEN1TP53 | |
| SCHEMBL10653053 | 1.00 | MAPT (0.85) | MAPTKMT2ACYP3A4MEN1TP53 | |
| Estradiol Propionate SCHEMBL30384276 | 0.92 | MAPT (1.00) | MAPTKMT2ACYP3A4MEN1TP53 | |
| Estradiol Propionate SCHEMBL30165166 | 0.92 | MAPT (1.00) | MAPTKMT2ACYP3A4MEN1TP53 | |
| Estradiol Propionate SCHEMBL480992 | 0.92 | MAPT (1.00) | MAPTKMT2ACYP3A4MEN1TP53 | |
| Estradiol Propionate SCHEMBL26659949 | 0.92 | MAPT (1.00) | MAPTKMT2ACYP3A4MEN1TP53 | |
| SCHEMBL11273115 | 0.91 | MAPT (0.83) | MAPTKMT2ACYP3A4MEN1TP53 | |
| SCHEMBL19286799 | 0.91 | MAPT (0.83) | MAPTKMT2ACYP3A4MEN1TP53 | |
| SCHEMBL19286020 | 0.91 | MAPT (0.71) | MAPTKMT2ACYP3A4MEN1TP53 | |
| SCHEMBL19286815 | 0.91 | MAPT (0.83) | MAPTKMT2ACYP3A4MEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | POLYNOVO BIOMATERIALS PTY LIMITED (AU) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287102-A1 | CHAIN EXTENDERS | UMPS, PUF60, SMCHD1 | MAPT 826/4885KMT2A 3905/4885CYP3A4 1817/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.