Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | PIM1 | P11309 | 3/20 | 0.50 |
| ▸ | PARP1 | P09874 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3032908 | 0.80 | PIM1 (0.80) | KDM4EPIM1MAPTATMADORA2A | |
| SCHEMBL28260510 | 0.77 | GCGR (0.49) | KDM4EMAPTHPGDMEN1ALDH1A1 | |
| SCHEMBL14385566 | 0.75 | PIM1 (0.48) | KDM4EPIM1PARP1MAPTPTGER2 | |
| SCHEMBL14385797 | 0.73 | KDM4E (0.49) | KDM4EPIM1PARP1MAPTADORA2A | |
| SCHEMBL4408790 | 0.73 | TAS2R38 (0.47) | KDM4EPARP1MAPTHPGDPKM | |
| SCHEMBL14439357 | 0.71 | KDM4E (0.66) | KDM4EPARP1MAPTATMADORA2A | |
| SCHEMBL6935142 | 0.70 | PIM1 (0.49) | KDM4EPIM1PARP1PTGER2MAPK14 | |
| SCHEMBL8222270 | 0.70 | KDM4E (0.59) | KDM4EPARP1MAPTATMADORA2A | |
| SCHEMBL14390904 | 0.69 | PARP1 (0.53) | KDM4EPIM1PARP1MAPTPTGER2 | |
| SCHEMBL13042312 | 0.67 | MAPT (0.46) | KDM4EPIM1PARP1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006070-A2 | COMPOUNDS AND COMBINATIONS THEREOF FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF USE THEREOF | ROSKAMP RESEARCH LLC (US) | 2008-01-10 | — | — | WO | disclosed |