SCHEMBL4408790

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8799476	0.87	KDM4E (0.44)	TAS2R38NOTUMKDM4EMAPTHPGD
	SCHEMBL9522651	0.81	CYP2E1 (0.42)	TAS2R38KDM4ESMN1; SMN2MEN1KMT2A
	SCHEMBL6756097	0.79	TAS2R38 (0.60)	TAS2R38NOTUMKDM4EMAPTSMN1; SMN2
	SCHEMBL8987259	0.77	TAS2R38 (0.44)	TAS2R38NOTUMKDM4EMAPTSMN1; SMN2
	SCHEMBL8222273	0.73	KDM4E (0.50)	KDM4EMAPTSMN1; SMN2HPGDALDH1A1
	SCHEMBL28043530	0.73	KDM4E (0.54)	KDM4EMAPTHPGDALDH1A1CYP3A4
	SCHEMBL28260510	0.72	GCGR (0.49)	KDM4EMAPTHPGDALDH1A1CYP3A4
	SCHEMBL31124	0.72	CYP3A4 (0.58)	KDM4EMAPTHPGDALDH1A1CYP3A4
	SCHEMBL3595434	0.72	TOP1 (0.56)	KDM4EMAPTSMN1; SMN2HPGDALDH1A1
	SCHEMBL8987160	0.71	CYP2E1 (0.53)	TAS2R38NOTUMKDM4EMAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.