Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.59 |
| ▸ | HTR3B | O95264 | 3/20 | 0.59 |
| ▸ | HTR3A | P46098 | 3/20 | 0.59 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.59 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.59 |
| ▸ | PNMT | P11086 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.50 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.49 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.49 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.49 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | AGXT | P21549 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1047900 | 0.94 | HTR3E (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL7740676 | 0.92 | HTR3E (0.56) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL1046534 | 0.92 | HTR3E (0.56) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL3030059 | 0.92 | HTR3E (0.56) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5584322 | 0.89 | TBXA2R (0.58) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL625264 | 0.87 | TAAR1 (0.63) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL5241228 | 0.87 | TAAR1 (0.68) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| Hydrochloric Acid SCHEMBL7753581 | 0.85 | TAAR1 (0.61) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL31567921 | 0.85 | TAAR1 (0.65) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL241880 | 0.84 | CYP4F2 (0.53) | TAAR1TBXA2RMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 172 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112980895-B | Enzymatic synthesis method of (R) -3-chloropropanol | 宿迁阿尔法科技有限公司 | 2023-09-26 | — | — | CN | claimed |
| CN-108383703-B | 3' -chlorophenylpropanol synthesis process | 兰州紫东药业有限公司 | 2021-08-03 | — | — | CN | claimed |
| CN-112980895-A | Enzymatic synthesis method of (R) -3-chlorophenylpropanol | 宿迁阿尔法科技有限公司 | 2021-06-18 | — | — | CN | claimed |
| CN-112708641-A | Chemical-enzymatic synthesis method of tomoxetine | 上海医药工业研究院 | 2021-04-27 | — | — | CN | claimed |
| CN-102584536-B | Method for asymmetrically catalyzing and synthesizing (R)-(+)-3-chlorine-phenylpropanol | GUANGXI XINJING TECHNOLOGY CO LTD | 2014-06-11 | — | — | CN | claimed |
| CN-102584536-A | Method for asymmetrically catalyzing and synthesizing (R)-(+)-3-chlorine-phenylpropanol | GUANGXI XINJING TECHNOLOGY CO LTD | 2012-07-18 | — | — | CN | claimed |
| WO-2000037425-A1 | METHOD FOR PRODUCING FLUOXETIN | SIEGFRIED CMS AG (CH) | 2000-06-29 | — | — | WO | claimed |
| EP-0743940-A1 | NEW COMPOUNDS WITH ANALGESIC AND LOCAL ANAESTHETIC EFFECT | Astra Aktiebolag (SE) | 1996-11-27 | — | — | EP | claimed |
| WO-1995021821-A1 | NEW COMPOUNDS WITH ANALGESIC AND LOCAL ANAESTHETIC EFFECT | ASTRA AKTIEBOLAG (SE) | 1995-08-17 | — | — | WO | claimed |
| US-20240166652-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | ABBVIE INC. | 2024-05-23 | — | — | US | disclosed |
| US-20240150318-A1 | PROTEASE INHIBITORS FOR TREATMENT OF CORONAVIRUS INFECTIONS | THE SCRIPPS RESEARCH INSTITUTE | 2024-05-09 | — | — | US | disclosed |
| EP-4356971-A2 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | Calico Life Sciences LLC (US) | 2024-04-24 | — | — | EP | disclosed |
| EP-4352040-A1 | PROTEASE INHIBITORS FOR THE TREATMENT OF CORONAVIRUS INFECTIONS | The Scripps Research Institute (US) | 2024-04-17 | — | — | EP | disclosed |
| CN-117794896-A | Protease inhibitors for the treatment of coronavirus infections | 斯克里普斯研究学院 | 2024-03-29 | — | — | CN | disclosed |
| EP-0025192-B1 | SUBSTITUTED OXIRANE CARBOXYLIC ACIDS, PROCESS FOR THEIR PREPARATION, THEIR USE AND MEDICINES CONTAINING THEM | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1983-05-11 | — | — | EP | disclosed |
| US-4324796-A | HYPOGLYCEMIC AGENTS, HYPOKETONEMIC AGENTS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-04-13 | — | — | US | disclosed |
| EP-0025192-A2 | Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1981-03-18 | — | — | EP | disclosed |
| US-4242347-A | Hypotensive indolylalkylpiperidyl guanidines and isoureas | CIBA-GEIGY CORPORATION (US) | 1980-12-30 | — | — | US | disclosed |
| US-4147786-A | HYPOTENSIVE | CIBA-GEIGY CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
| US-4073911-A | ANTIHYPERTENSIVE AGENTS | CIBA-GEIGY CORPORATION (US) | 1978-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166652-A1 | MODULATORS OF THE INTEGRATED STRESS PATHWAY | ATF4, ATF1, DDIT3 | HTR3E 2823/4885HTR3B 1795/4885HTR3A 2866/4885 |
| US-20240150318-A1 | PROTEASE INHIBITORS FOR TREATMENT OF CORONAVIRUS INFECTIONS | ACE, ACE2, TMPRSS2 | HTR3E 968/4885HTR3B 738/4885HTR3A 1246/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.