SCHEMBL822282

SCHEMBL822282

C=CCN(CC=C)C(=C)C

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP1A2 P05177 1/20 0.32
DPP4 P27487 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24636173 0.87 ALDH1A1 (0.38) ALDH1A1TSHRTP53CYP1A2
SCHEMBL13979997 0.81 CA12 (0.37) ALDH1A1DPP4
SCHEMBL6257968 0.79 ALDH1A1 (0.44) ALDH1A1TSHRTP53CYP1A2DPP4
SCHEMBL3459159 0.79 ALDH1A1 (0.44) ALDH1A1TSHRTP53CYP1A2DPP4
SCHEMBL22591335 0.78 ALDH1A1 (0.39) ALDH1A1TSHRTP53HSD17B10TDP1
SCHEMBL6253298 0.74 ALDH1A1 (0.41) ALDH1A1CYP1A2DPP4SMN1; SMN2
SCHEMBL11616346 0.74 ALDH1A1 (0.52) ALDH1A1TSHRTDP1DPP4SMN1; SMN2
SCHEMBL24811243 0.74
SCHEMBL173228 0.74 ALDH1A1 (0.52) ALDH1A1TSHRTDP1DPP4SMN1; SMN2
SCHEMBL6253294 0.74 ALDH1A1 (0.41) ALDH1A1CYP1A2DPP4SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2059539-B1 USE OF A GLYOXYLATED VINYLAMIDE POLYMER AS DRY AND WET STRENGTH AID FOR PAPER BASF SE (DE) 2011-11-16 EP claimed
CN-110268114-B High molecular weight temporary wet strength resins for paper 索理思科技开曼公司 2022-12-13 CN disclosed
CN-113785029-A Compositions and methods for increasing wet and dry paper strength 索理思科技开曼公司 2021-12-10 CN disclosed
EP-3130615-B1 GLYOXALATION OF VINYLAMIDE POLYMER SOLENIS TECHNOLOGIES CAYMAN LP (KY) 2021-03-10 EP disclosed
EP-3130615-A1 GLYOXALATION OF VINYLAMIDE POLYMER BASF SE (DE) 2017-02-15 EP disclosed
US-20160317435-A1 METHODS AND COMPOSITIONS FOR TRANSDERMAL DELIVERY OF CAFFEINE IN THE FORM OF SOLUTIONS OR SUSPENSIONS SPRAYABLE HOLDINGS, INC. 2016-11-03 US disclosed
EP-2386579-B1 GLYOXALATION OF VINYLAMIDE POLYMER BASF SE (DE) 2016-10-12 EP disclosed
EP-2386580-B1 GLYOXALATION OF VINYLAMIDE POLYMER BASF SE (DE) 2016-10-12 EP disclosed
US-9211249-B2 Methods and compositions for transdermal delivery of caffeine in the form of solutions or suspensions SPRAYABLE HOLDINGS, INC. 2015-12-15 US disclosed
US-20140256749-A1 METHODS AND COMPOSITIONS FOR TRANSDERMAL DELIVERY OF CAFFEINE IN THE FORM OF SOLUTIONS OR SUSPENSIONS SPRAYABLE HOLDINGS, INC. 2014-09-11 US disclosed
EP-2386580-A2 Glyoxalation of vinylamide polymer BASF SE (DE) 2011-11-16 EP disclosed
EP-2059539-B1 USE OF A GLYOXYLATED VINYLAMIDE POLYMER AS DRY AND WET STRENGTH AID FOR PAPER BASF SE (DE) 2011-11-16 EP disclosed
US-8039031-B2 Tuning the electromagnetic field relating to a sample parameter and monitoring a sample quality; particularly relating to drying of corn with high energy efficiency to produce high quality dried corn, with a low to very low level of cracks. Energy Systems Engineering LLC (US) 2011-10-18 US disclosed
US-20110224374-A1 GLYOXALATED N-VINYLAMINE BASF SE (DE) 2011-09-15 US disclosed
EP-2343324-A1 Glyoxalated poly(n-vinylamine) BASF SE (DE) 2011-07-13 EP disclosed
EP-2215130-A2 GLYOXALATED N-VINYLAMINE BASF SE (DE) 2010-08-11 EP disclosed
EP-1107997-B1 POLYMER PRODUCTION QINETIQ LTD (GB) 2010-01-27 EP disclosed
EP-2059539-A2 GLYOXALATION OF VINYLAMIDE POLYMER Ciba Holding Inc. (CH) 2009-05-20 EP disclosed
WO-2009059725-A2 GLYOXALATED POLY (N-VINYLAMINE) BASF SE (DE) 2009-05-14 WO disclosed
WO-2008028865-A2 GLYOXALATION OF VINYLAMIDE POLYMER CIBA HOLDING INC. (GB) 2008-03-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140256749-A1 METHODS AND COMPOSITIONS FOR TRANSDERMAL DELIVERY OF CAFFEINE IN THE FORM OF SOLUTIONS OR SUSPENSIONS TES, CCR7, CES2 ALDH1A1 1876/4885TSHR 3430/4885TP53 3895/4885
US-20160317435-A1 METHODS AND COMPOSITIONS FOR TRANSDERMAL DELIVERY OF CAFFEINE IN THE FORM OF SOLUTIONS OR SUSPENSIONS TES, CCR7, CES2 ALDH1A1 1876/4885TSHR 3430/4885TP53 3895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.