SCHEMBL822308

SCHEMBL822308

CCCCCC1=C(CCCCC)CCC1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCD O00767 1/20 0.43
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
TSHR P16473 1/20 0.37
THRB P10828 1/20 0.37
CCR5 P51681 3/20 0.35
CYP3A4 P08684 3/20 0.34
PTGS2 P35354 3/20 0.34
NPC1 O15118 3/20 0.33
LMNA P02545 3/20 0.33
HTT P42858 3/20 0.33
RAB9A P51151 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
S1PR2 O95136 2/20 0.33
CYP1A2 P05177 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
ALDH1A1 P00352 2/20 0.33
SLC2A1 P11166 2/20 0.33
ESR1 P03372 2/20 0.33
ADRA2A P08913 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5346762 0.97 SCD (0.47) SCDMEN1KMT2ATSHRTHRB
SCHEMBL10985090 0.93 SCD (0.53) SCDMEN1KMT2ATSHRTHRB
SCHEMBL20339953 0.92 MEN1 (0.42) SCDMEN1KMT2ATSHRTHRB
SCHEMBL678379 0.92 MEN1 (0.42) SCDMEN1KMT2ATSHRTHRB
SCHEMBL2335039 0.88 SCD (0.46) SCDMEN1KMT2ATSHRTHRB
SCHEMBL4452153 0.86 MEN1 (0.36) SCDMEN1KMT2ATSHRTHRB
SCHEMBL9340336 0.86 SCD (0.50) SCDMEN1KMT2ATSHRTHRB
SCHEMBL3945297 0.85 SCD (0.38) SCDMEN1KMT2ATSHRTHRB
SCHEMBL7934433 0.84 SCD (0.41) SCDMEN1KMT2ACYP3A4PTGS2
SCHEMBL31337396 0.84 SCD (0.41) SCDMEN1KMT2ACYP3A4PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 77 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1802726-B1 PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF ADVANCED POLYMERIK PTY LTD (AU) 2011-11-30 EP claimed
WO-2009121148-A1 DYE COMPRISING FUNCTIONAL SUBSTITUENT ADVANCED POLYMERIK PTY LTD (AU) 2009-10-08 WO claimed
US-20090093601-A1 Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof POLYMERS AUSTRALIA PTY LIMITED (AU) 2009-04-09 US claimed
EP-1802726-A4 PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF POLYMERS AUSTRALIA PTY LTD (AU) 2008-04-30 EP claimed
EP-1802726-A1 PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF Polymers Australia PTY Limited (AU) 2007-07-04 EP claimed
WO-2006024099-A1 PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF POLYMERS AUSTRALIA PTY LIMITED (AU) 2006-03-09 WO claimed
US-20240228436-A1 POLYSUBSTITUTED SELENIUM-CONTAINING CYCLOPENT(HEX)ENE SKELETON DERIVATIVE AND SYNTHESIS METHOD THEREOF SOOCHOW UNIVERSITY (CN) 2024-07-11 US disclosed
EP-4326543-A1 METHOD FOR PRODUCING AN OPTICAL MODULE AND OPTICAL MODULE DELO Industrie Klebstoffe GmbH & Co. KGaA (DE) 2024-02-28 EP disclosed
WO-2023220463-A1 METHODS OF FORMING AN OBJECT IN A VOLUME OF A PHOTOHARDENABLE COMPOSITION QUADRATIC 3D, INC. (US) 2023-11-16 WO disclosed
WO-2023279426-A1 POLYSUBSTITUTED SELENIUM-CONTAINING CYCLOPENT(HEX)ENE FRAMEWORK DERIVATIVE AND SYNTHESIS METHOD THEREFOR 苏州大学 2023-01-12 WO disclosed
CN-108690045-B Diarylethene compounds and uses thereof 首诺加拿大公司 2022-08-30 CN disclosed
CN-113429325-B Polysubstituted selenium-containing cyclopentene (hexene) skeleton derivative and synthetic method thereof 苏州大学 2022-05-17 CN disclosed
CN-111040110-B Force-induced response dynamic polymer and application thereof 厦门天策材料科技有限公司 2022-03-11 CN disclosed
US-5811416-A ADMINISTERING TO TREAT DISORDERS SUCH AS DYSMENORRHEA, PRETERM LABOR, PREECLAMPSIA, OR FETAL GROWTH RETARDATION; ALSO HORMONE REPLACEMENT THERAPY, HYPERTENSION BOARD OF REGENTS THE UNIVERSITY OF TEXAS SYSTEM (US) 1998-09-22 US disclosed
EP-0859642-A2 METHOD OF DETECTING CYCLOOXYGENASE-2 G.D. SEARLE & CO. (US) 1998-08-26 EP disclosed
WO-1997014679-A2 METHOD OF DETECTING CYCLOOXYGENASE-2 G.D. SEARLE & CO. (US) 1997-04-24 WO disclosed
US-5576339-A Pyridyl substituted cyclopentadienes for the treatment of inflamation HUANG HORNG-CHIH (US) 1996-11-19 US disclosed
WO-1995030656-A1 SUBSTITUTED CYCLOPENTADIENYL COMPOUNDS FOR THE TREATMENT OF INFLAMMATION G.D. SEARLE & CO. (US) 1995-11-16 WO disclosed
US-5418254-A Side effect reduction G. D. SEARLE & CO. (US) 1995-05-23 US disclosed
US-5344991-A Sulfonyl or sulfamyl derivatives for treatment of arthritis and pain G.D. SEARLE & CO. (US) 1994-09-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240228436-A1 POLYSUBSTITUTED SELENIUM-CONTAINING CYCLOPENT(HEX)ENE SKELETON DERIVATIVE AND SYNTHESIS METHOD THEREOF SCLY, SELENOI, SELE SCD 54/4885MEN1 3463/4885KMT2A 4165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.