Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 14/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.33 |
| ▸ | ESR1 | P03372 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1008895 | 0.90 | GRM5 (0.42) | GRM5ALDH1A1TDP1GAAMAPT | |
| SCHEMBL1009713 | 0.90 | GRM5 (0.47) | GRM5ALDH1A1TDP1GAAMAPT | |
| SCHEMBL3813142 | 0.79 | GRM5 (0.33) | GRM5 | |
| SCHEMBL3819163 | 0.79 | MAPK1 (0.33) | — | |
| SCHEMBL8212864 | 0.78 | F11 (0.38) | GRM5ALDH1A1TDP1GAAMAPT | |
| SCHEMBL8215209 | 0.78 | ESR2 (0.37) | GRM5ALDH1A1TDP1GAAMAPT | |
| SCHEMBL12952498 | 0.78 | GRM5 (0.37) | GRM5ALDH1A1TDP1GAAMAPT | |
| SCHEMBL1011176 | 0.77 | GRM5 (0.42) | GRM5ALDH1A1TDP1GAAMAPT | |
| SCHEMBL1011577 | 0.77 | GRM5 (0.47) | GRM5ALDH1A1TDP1GAAMAPT | |
| SCHEMBL8221373 | 0.76 | ALDH1A1 (0.41) | GRM5ALDH1A1TDP1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008015269-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THEIR USE AS MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-02-07 | — | — | WO | disclosed |