Trichlormethine

Trichlormethine

SCHEMBL8224

ClCCN(CCCl)CCCl

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.91
MAPT P10636 2/20 0.47
TSHR P16473 4/20 0.44
TP53 P04637 1/20 0.44
HTT P42858 1/20 0.44
HBB P68871 1/20 0.44
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 2/20 0.36
TDP1 Q9NUW8 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
NFKB1 P19838 1/20 0.30
CYP2C19 P33261 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trichlormethine SCHEMBL338967 0.95 LMNA (1.00) LMNAMAPTTSHRTP53HTT
Trichlormethine SCHEMBL1820371 0.95 LMNA (0.83) LMNAMAPTTSHRTP53HTT
Trichlormethine SCHEMBL1651598 0.91 LMNA (0.77) LMNAMAPTTSHRTP53HTT
SCHEMBL12552521 0.88 LMNA (0.71) LMNAMAPTTSHRTP53HTT
SCHEMBL7039551 0.84 LMNA (0.67) LMNAMAPTTSHRTP53HTT
SCHEMBL12552525 0.84 LMNA (0.67) LMNAMAPTTSHRTP53HTT
SCHEMBL10540029 0.84 LMNA (0.67) LMNAMAPTTSHRTP53HTT
SCHEMBL2615232 0.82 LMNA (0.62) LMNAMAPTTSHRTP53HTT
SCHEMBL1252794 0.82 LMNA (0.62) LMNAMAPTTSHRTP53HTT
SCHEMBL6048117 0.82 LMNA (0.62) LMNAMAPTTSHRTP53HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 18317 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4743490-A1 HUMANIZED ANTI-CD7 ANTIBODY Christian-Albrechts-Universität zu Kiel (DE) 2026-05-20 EP claimed
WO-2026099502-A1 NOVEL DRUG CONJUGATES FOR TESTING CELLULAR DRUG UPTAKE Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 2026-05-15 WO claimed
US-20260108619-A1 CONJUGATION LINKERS, CELL BINDING MOLECULE-DRUG CONJUGATES CONTAINING THE LINKERS, METHODS OF MAKING AND USES SUCH CONJUGATES WITH THE LINKERS HANGZHOU DAC BIOTECH CO., LTD. (CN) 2026-04-23 US claimed
US-20260085100-A1 METHODS OF ANTIGEN PRODUCTION THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY (US) 2026-03-26 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
EP-4698185-A1 METHODS AND SYSTEMS FOR IMPROVING ANTI-CANCER THERAPIES Osasuna Therapeutics SA (CH) 2026-02-25 EP claimed
EP-4694909-A1 METHODS OF MODULATING THE EPITHELIAL-MESENCHYMAL TRANSITION RS Oncology, LLC (US) 2026-02-18 EP claimed
EP-4687999-A1 TROP2 CONJUGATED BIOLOGICAL MOLECULES, PHARMACEUTICAL COMPOSITIONS AND METHODS OBI Pharma, Inc. (TW) 2026-02-11 EP claimed
EP-4676544-A1 ANTIBODY-DRUG CONJUGATE COMPRISING ANTIBODIES AGAINST HUMAN L1CAM AND USES THEREOF LigaChem Biosciences Inc. (KR) 2026-01-14 EP claimed
EP-3277381-B1 NITROBENZYL DERIVATIVES OF ANTI-CANCER AGENTS OBI PHARMA INC (TW) 2026-01-07 EP claimed
WO-1999058126-B1 USE OF NEOMYCIN FOR TREATING ANGIOGENESIS-RELATED DISEASES ENDOWMENT RES INHUMAN BIOLOGY (US) 2000-02-17 WO claimed
WO-1999058126-A1 USE OF NEOMYCIN FOR TREATING ANGIOGENESIS-RELATED DISEASES THE ENDOWMENT FOR RESEARCH IN HUMAN BIOLOGY, INC. (US) 1999-11-18 WO claimed
JP-2907474-B2 1999-06-21 JP claimed
EP-0439540-B1 ANTIBODY CONJUGATES WITH TWO OR MORE COVALENTLY LINKED FC REGIONS 3I RES EXPL LTD (GB) 1995-06-28 EP claimed
EP-0439540-A1 ANTIBODY CONJUGATES WITH TWO OR MORE COVALENTLY LINKED FC REGIONS. 3I RES EXPL LTD (GB) 1991-08-07 EP claimed
WO-1990004413-A1 ANTIBODY CONJUGATES WITH TWO OR MORE COVALENTLY LINKED Fc REGIONS 3I RESEARCH EXPLOITATION LIMITED (GB) 1990-05-03 WO claimed
US-4481373-A CATALYTIC OXIDATION OF OLEFINS IN PRESENCE OF TERTIARY AMINE OF AMIDE TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1984-11-06 US claimed
EP-0005094-B1 PROCESS FOR THE PREPARATION OF TRIS-(POLYOXAALKYL)-AMINES RHONE-POULENC INDUSTRIES (FR) 1980-10-29 EP claimed
EP-0005090-B1 PROCESS FOR THE PREPARATION OF TRIS(8-HYDROXY-3,6-DIOXA-OCTYL)-AMINE, AND THE COMPOUND OBTAINED BY THIS PROCESS RHONE-POULENC INDUSTRIES (FR) 1980-10-01 EP claimed
US-4073633-A Topical nitrogen fertilization method UNION OIL COMPANY OF CALIFORNIA (US) 1978-02-14 US claimed