Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | RPA1 | P27694 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.35 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17007116 | 0.83 | CES2 (0.41) | DPP4KDM4E | |
| SCHEMBL28299440 | 0.83 | DPP4 (0.58) | DPP4ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL24456032 | 0.79 | DPP4 (0.54) | DPP4ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL1358784 | 0.79 | DPP4 (0.54) | DPP4ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL25679318 | 0.78 | CA1 (0.46) | DPP4ALDH1A1KDM4EHSD17B10GAA | |
| SCHEMBL29181700 | 0.78 | DPP4 (0.52) | DPP4ALDH1A1KDM4EHSD17B10TP53 | |
| Potassium SCHEMBL30811378 | 0.78 | DPP4 (0.52) | DPP4ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL24717969 | 0.78 | CYP1A2 (0.41) | ALDH1A1KDM4ETSHRALOX15CASP1 | |
| SCHEMBL1467095 | 0.77 | DPP4 (0.50) | DPP4ALDH1A1KDM4EHSD17B10TP53 | |
| SCHEMBL31193466 | 0.76 | DPP4 (0.60) | DPP4ALDH1A1KDM4EHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119775121-A | Synthetic method of multi-halogen substituted fluorine-containing 2-bromobenzoic acid compound | 上海毕得医药科技股份有限公司 | 2025-04-08 | — | — | CN | disclosed |
| US-RE49556-E1 | Compounds and compositions as protein kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2023-06-20 | — | — | US | disclosed |
| US-20230116233-A1 | Compounds And Compositions As Protein Kinase Inhibitors | ARRAY BIOPHARMA INC (US) | 2023-04-13 | — | — | US | disclosed |
| US-20200323852-A1 | Compounds And Compositions As Protein Kinase Inhibitors | IRM LLC (BM) | 2020-10-15 | — | — | US | disclosed |
| US-10576080-B2 | Compounds and compositions as protein kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2020-03-03 | — | — | US | disclosed |
| US-10568884-B2 | Compounds and compositions as protein kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2020-02-25 | — | — | US | disclosed |
| US-20180297986-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2018-10-18 | — | — | US | disclosed |
| US-20180297985-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2018-10-18 | — | — | US | disclosed |
| US-10005761-B2 | Compounds and compositions as protein kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2018-06-26 | — | — | US | disclosed |
| US-9850229-B2 | Compounds and compositions as protein kinase inhibitors | ARRAY BIOPHARMA, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-20160120866-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | NOVARTIS AG (CH) | 2016-05-05 | — | — | US | disclosed |
| US-9314464-B2 | Compounds and compositions as protein kinase inhibitors | NOVARTIS AG (CH) | 2016-04-19 | — | — | US | disclosed |
| EP-2470526-B1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2014-05-28 | — | — | EP | disclosed |
| EP-2727918-A1 | Compounds and Compositions as Protein Kinase Inhibitors | IRM LLC (BM) | 2014-05-07 | — | — | EP | disclosed |
| US-20130296318-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA, INC. | 2013-11-07 | — | — | US | disclosed |
| US-8501758-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2013-08-06 | — | — | US | disclosed |
| CN-102725283-A | Compounds and compositions as protein kinase inhibitors | IRM LLC | 2012-10-10 | — | — | CN | disclosed |
| EP-2470526-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2012-07-04 | — | — | EP | disclosed |
| US-20110306625-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | NOVARTIS AG (CH) | 2011-12-15 | — | — | US | disclosed |
| WO-2011025927-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2011-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200323852-A1 | Compounds And Compositions As Protein Kinase Inhibitors | BRAF, RAF1, ARAF | DPP4 3889/4885ALDH1A1 4023/4885KDM4E 2572/4885 |
| US-20110306625-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | BRAF, RAF1, ARAF | DPP4 3889/4885ALDH1A1 4023/4885KDM4E 2572/4885 |
| US-20130296318-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | BRAF, RAF1, ARAF | DPP4 3889/4885ALDH1A1 4023/4885KDM4E 2572/4885 |
| US-10005761-B2 | Compounds and compositions as protein kinase inhibitors | BRAF, RAF1, ARAF | DPP4 3889/4885ALDH1A1 4023/4885KDM4E 2572/4885 |
| US-10568884-B2 | Compounds and compositions as protein kinase inhibitors | BRAF, RAF1, ARAF | DPP4 3889/4885ALDH1A1 4023/4885KDM4E 2572/4885 |
| US-20180297985-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | BRAF, RAF1, ARAF | DPP4 3889/4885ALDH1A1 4023/4885KDM4E 2572/4885 |
| US-20230116233-A1 | Compounds And Compositions As Protein Kinase Inhibitors | BRAF, RAF1, ARAF | DPP4 3889/4885ALDH1A1 4023/4885KDM4E 2572/4885 |
| US-20180297986-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | BRAF, RAF1, ARAF | DPP4 3889/4885ALDH1A1 4023/4885KDM4E 2572/4885 |
| US-10576080-B2 | Compounds and compositions as protein kinase inhibitors | BRAF, RAF1, ARAF | DPP4 3889/4885ALDH1A1 4023/4885KDM4E 2572/4885 |
| US-20160120866-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | BRAF, RAF1, ARAF | DPP4 3889/4885ALDH1A1 4023/4885KDM4E 2572/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.