Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.67 |
| ▸ | LOX | P28300 | 1/20 | 0.65 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057494 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2NOTUMIDO1 | |
| SCHEMBL8180170 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2NOTUMIDO1 | |
| SCHEMBL29988849 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2NOTUMIDO1 | |
| SCHEMBL8256658 | 0.80 | LOXL2 (1.00) | LOXL2LOXKCNQ2NOTUMIDO1 | |
| SCHEMBL131880 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2NOTUMIDO1 | |
| SCHEMBL30119999 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2NOTUMIDO1 | |
| SCHEMBL16388355 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2NOTUMIDO1 | |
| SCHEMBL16047057 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2NOTUMIDO1 | |
| SCHEMBL30885142 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2NOTUMIDO1 | |
| Hydrochloric Acid SCHEMBL19584339 | 0.78 | LOXL2 (0.68) | LOXL2LOXKCNQ2NOTUMIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008002671-A2 | METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-01-03 | — | — | WO | disclosed |