Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.67 |
| ▸ | LOX | P28300 | 1/20 | 0.65 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.48 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.37 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.37 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.37 |
| ▸ | MMP13 | P45452 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | VNN1 | O95497 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.35 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30119999 | 1.00 | LOXL2 (0.67) | LOXL2LOXKCNQ2TYMSNOTUM | |
| SCHEMBL31375482 | 0.80 | LOXL2 (0.49) | LOXL2LOXKCNQ2NOTUMIDO1 | |
| SCHEMBL8224465 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2TYMSNOTUM | |
| SCHEMBL131880 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2TYMSNOTUM | |
| SCHEMBL29988849 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2TYMSNOTUM | |
| SCHEMBL30885142 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2TYMSNOTUM | |
| SCHEMBL16047057 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2TYMSNOTUM | |
| SCHEMBL8256658 | 0.80 | LOXL2 (1.00) | LOXL2LOXKCNQ2TYMSNOTUM | |
| SCHEMBL8180170 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2TYMSNOTUM | |
| SCHEMBL9057494 | 0.80 | LOXL2 (0.67) | LOXL2LOXKCNQ2TYMSNOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12428420-B2 | Tricyclic heterocycles as FGFR inhibitors | INCYTE CORPORATION (US) | 2025-09-30 | — | — | US | disclosed |
| EP-4352060-A1 | TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS | Incyte Corporation (US) | 2024-04-17 | — | — | EP | disclosed |
| US-20230002384-A1 | TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS | INCYTE CORPORATION | 2023-01-05 | — | — | US | disclosed |
| WO-2022261159-A1 | TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS | INCYTE CORPORATION (US) | 2022-12-15 | — | — | WO | disclosed |
| US-10681909-B2 | Herbicidal triazoles | FMC CORPORATION (US) | 2020-06-16 | — | — | US | disclosed |
| US-20170354149-A1 | HERBICIDAL TRIAZOLES | FMC CORPORATION | 2017-12-14 | — | — | US | disclosed |
| EP-3185684-A1 | HERBICIDAL TRIAZOLES | E. I. du Pont de Nemours and Company (US) | 2017-07-05 | — | — | EP | disclosed |
| US-9695154-B2 | Heteroaryl inhibitors of sumo activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| US-9695154-B2 | Heteroaryl inhibitors of sumo activating enzyme | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2017-07-04 | — | — | US | disclosed |
| CN-106659159-A | Herbicidal triazoles | 杜邦公司 | 2017-05-10 | — | — | CN | disclosed |
| US-20160355504-A1 | HETEROARYL INHIBITORS OF SUMO ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-12-08 | — | — | US | disclosed |
| US-20160355504-A1 | HETEROARYL INHIBITORS OF SUMO ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2016-12-08 | — | — | US | disclosed |
| WO-2016033285-A1 | HERBICIDAL TRIAZOLES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-03-03 | — | — | WO | disclosed |
| US-20150105252-A1 | SUBSTITUTED PYRAZOLES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY | 2015-04-16 | — | — | US | disclosed |
| WO-2015002994-A2 | HETEROARYL COMPOUNDS USEFUL AS INHIBITORS OF SUMO ACTIVATING ENZYME | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-01-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170354149-A1 | HERBICIDAL TRIAZOLES | CYP1A1, CYP1B1, CYP4X1 | LOXL2 1812/4885LOX 905/4885KCNQ2 2496/4885 |
| US-12428420-B2 | Tricyclic heterocycles as FGFR inhibitors | FGFR3, FGFR1, FGFR2 | LOXL2 2606/4885LOX 2737/4885KCNQ2 4255/4885 |
| US-10681909-B2 | Herbicidal triazoles | CYP1A1, CYP1B1, CYP4X1 | LOXL2 1812/4885LOX 905/4885KCNQ2 2496/4885 |
| US-20160355504-A1 | HETEROARYL INHIBITORS OF SUMO ACTIVATING ENZYME | SAE1, SUMO2, SUMO1 | LOXL2 2836/4885LOX 2724/4885KCNQ2 3690/4885 |
| US-20150105252-A1 | SUBSTITUTED PYRAZOLES AS HERBICIDES | CYP1B1, CYP1A1, DDT | LOXL2 2787/4885LOX 986/4885KCNQ2 725/4885 |
| US-20230002384-A1 | TRICYCLIC HETEROCYCLES AS FGFR INHIBITORS | FGFR3, FGFR1, FGFR2 | LOXL2 2606/4885LOX 2737/4885KCNQ2 4255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.