Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 8/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 8/20 | 0.52 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.52 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | DRD1 | P21728 | 5/20 | 0.50 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8048509 | 0.90 | IGF1R (0.69) | IGF1RALOX15ESR1ESR2GRIN1 | |
| Methylamine SCHEMBL27525680 | 0.85 | ESR1 (0.50) | ESR1ESR2DRD2CYP19A1 | |
| SCHEMBL24899246 | 0.83 | KDM1A (0.49) | IGF1RALOX15 | |
| SCHEMBL22072985 | 0.83 | KDM1A (0.49) | IGF1RALOX15 | |
| SCHEMBL27909263 | 0.83 | KDM1A (0.49) | IGF1RALOX15 | |
| Phenol SCHEMBL7789542 | 0.81 | SIGMAR1 (0.54) | IGF1RALOX15DRD1DRD2 | |
| SCHEMBL8528885 | 0.80 | ESR1 (0.45) | IGF1RALOX15ESR1ESR2CYP19A1 | |
| SCHEMBL8222945 | 0.80 | KDM1A (0.47) | ESR1ESR2CYP19A1 | |
| SCHEMBL9418172 | 0.79 | ESR1 (0.56) | IGF1RALOX15ESR1ESR2CYP19A1 | |
| SCHEMBL30458942 | 0.79 | ESR1 (0.63) | ESR1ESR2DRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2475649-A1 | INDENONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Korea Research Institute Of Chemical Technology (KR) | 2012-07-18 | — | — | EP | disclosed |
| WO-2011030955-A1 | INDENONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2011-03-17 | — | — | WO | disclosed |