Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8217912 | 0.85 | GPR119 (0.40) | NR1H2GPR119MEN1KMT2AALDH1A1 | |
| SCHEMBL11350163 | 0.81 | NR1H2 (0.46) | NR1H2NPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL8221410 | 0.81 | NR1H2 (0.43) | NR1H2GPR119ALDH1A1 | |
| SCHEMBL12220055 | 0.78 | NR1H2 (0.43) | NR1H2GPR119NPC1RAB9AALDH1A1 | |
| SCHEMBL11348613 | 0.73 | MAPT (0.41) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3079561 | 0.73 | MAPT (0.41) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3079557 | 0.73 | MAPT (0.41) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL11349724 | 0.73 | MAPT (0.41) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL3992059 | 0.73 | MAPT (0.41) | MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL4940056 | 0.73 | GPR119 (0.46) | NR1H2GPR119MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007146719-A2 | 2-AMINOCARBONYLPHENYLAMINO-2-PHENYLACETAMIDES AS FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2007-12-21 | — | — | WO | disclosed |