Sugi Predict

Sugi Predict / Compounds / SCHEMBL4940056

SCHEMBL4940056

SCHEMBL4940056

CC(C)(C)OC(=O)N1CCC(C(=O)O)C1c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ GPR119 Q8TDV5 1/20 0.46
▸ RIPK1 Q13546 3/20 0.46
▸ RORC P51449 1/20 0.44
▸ NR1H2 P55055 5/20 0.43
▸ NR1H3 Q13133 4/20 0.43
▸ RXRA P19793 2/20 0.43
▸ MEN1 O00255 1/20 0.43
▸ KMT2A Q03164 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.42
▸ PKM P14618 1/20 0.42
▸ HCRTR2 O43614 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ ABCB1 P08183 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4940048 1.00 GPR119 (0.46) GPR119RIPK1RORCNR1H2NR1H3
SCHEMBL4940062 1.00 GPR119 (0.46) GPR119RIPK1RORCNR1H2NR1H3
SCHEMBL17922881 0.92 RIPK1 (0.51) GPR119RIPK1RORCNR1H2NR1H3
SCHEMBL25411250 0.90 GPR119 (0.44) GPR119RIPK1RORCNR1H2NR1H3
SCHEMBL22805991 0.88 SLC6A2 (0.47) GPR119RIPK1NR1H2NR1H3RXRA
SCHEMBL14068810 0.86 GPR119 (0.48) GPR119RIPK1RORCNR1H2NR1H3
SCHEMBL4932763 0.85 MEN1 (0.45) GPR119RIPK1MEN1KMT2APKM
SCHEMBL4932770 0.85 MEN1 (0.45) GPR119RIPK1MEN1KMT2APKM
SCHEMBL14068811 0.85 MEN1 (0.45) GPR119RIPK1MEN1KMT2APKM
SCHEMBL4939817 0.85 MEN1 (0.45) GPR119RIPK1MEN1KMT2APKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12331034-B2 Substituted pyrrolidine amides V GRUENENTHAL GMBH (DE) 2025-06-17 — — US disclosed
US-20250179103-A1 6-OXODECAHYDROPYRROLO[1,2-A][1,5]DIAZOCINE AND 6-OXODECAHYDRO-4H-PYRROLO[2,1-D][1,5]THIAZOCINE DERIVATIVES AS STAT3 AND STAT6 MODULATORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS RECLUDIX PHARMA, INC. 2025-06-05 — — US disclosed
CN-119301127-A 6-Oxo-decahydro pyrrolo [1,2-a ] [1,5] diazocine and 6-oxo-decahydro-4H-pyrrolo [2,1-d ] [1,5] thiaazacine derivatives as modulators of STAT3 and STAT6 for the treatment of cancer and inflammatory conditions 瑞克鲁迪克斯制药股份有限公司 2025-01-10 — — CN disclosed
WO-2023164680-A1 6-OXODECAHYDROPYRROLO[1,2-A][1,5]DIAZOCINE AND 6-OXODECAHYDRO-4H-PYRROLO[2,1-D][1,5]THIAZOCINE DERIVATIVES AS STAT3 AND STAT6 MODULATORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS RECLUDIX PHARMA, INC. (US) 2023-08-31 — — WO disclosed
EP-3986886-A2 SUBSTITUTED PYRROLIDINE AMIDES V Grünenthal GmbH (DE) 2022-04-27 — — EP disclosed
US-20220106294-A1 SUBSTITUTED PYRROLIDINE AMIDES V GRUENENTHAL GMBH (DE) 2022-04-07 — — US disclosed
US-20220106294-A1 SUBSTITUTED PYRROLIDINE AMIDES V GRUENENTHAL GMBH (DE) 2022-04-07 — — US disclosed
WO-2020254552-A2 SUBSTITUTED PYRROLIDINE AMIDES V Grünenthal GmbH (DE) 2020-12-24 — — WO disclosed
US-20080221151-A1 3-AMINO-2-PHENYLPYRROLIDINE DERIVATIVES HUMPHREY JOHN MICHAEL 2008-09-11 — — US disclosed
US-7381741-B2 In which the amino is substituted by arylmethyl- or heteroarylmethyl- group, e.g., 2-Methoxybenzyl)-(2-phenylpyrrolidin-3-yl)-amine and 5-{[2-(3-Chloro-phenyl)-pyrrolidin-3-ylamino]-methyl}-6-methoxy-3-methyl-1,1a,3,7b-tetrahydro-3-aza-cyclopropa[a]naphalen-2-one; neurokinin 1 (Substance P) inhititors PFIZER INC (US) 2008-06-03 — — US disclosed
EP-1753718-A1 3-AMINO-2-PHENYLPYRROLIDINE DERIVATIVES Pfizer Products Incorporated (US) 2007-02-21 — — EP disclosed
EP-1372653-B1 ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS MERCK & CO INC (US) 2006-10-04 — — EP disclosed
US-7015235-B2 Acylated piperidine derivatives as melanocortin-4 receptor agonists MERCK & CO., INC. (US) 2006-03-21 — — US disclosed
US-20060035935-A1 Acylated piperidine derivatives as melanocortin-4 receptor agonists GOULET MARK T 2006-02-16 — — US disclosed
US-20050288358-A1 3-amino-2-phenylpyrrolidine derivatives PFIZER INC. 2005-12-29 — — US disclosed
WO-2005115976-A1 3-AMINO-2-PHENYLPYRROLIDINE DERIVATIVES PFIZER PRODUCTS INC. (US) 2005-12-08 — — WO disclosed
EP-1372653-A4 ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS MERCK & CO INC (US) 2005-10-05 — — EP disclosed
US-20040097546-A1 Acylated piperidine derivatives as melanocortin-4 receptor agonists MERCK SHARP & DOHME CORP. 2004-05-20 — — US disclosed
EP-1372653-A2 ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS Merck & Co., Inc. (US) 2004-01-02 — — EP disclosed
WO-2002068387-A2 ACYLATED PIPERIDINE DERIVATIVES AS MELANOCORTIN-4 RECEPTOR AGONISTS MERCK & CO., INC. (US) 2002-09-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250179103-A1 6-OXODECAHYDROPYRROLO[1,2-A][1,5]DIAZOCINE AND 6-OXODECAHYDRO-4H-PYRROLO[2,1-D][1,5]THIAZOCINE DERIVATIVES AS STAT3 AND STAT6 MODULATORS FOR THE TREATMENT OF CANCER AND INFLAMMATORY CONDITIONS STAT6, STAT3, STAT1 GPR119 343/4885RIPK1 1172/4885RORC 116/4885
US-20220106294-A1 SUBSTITUTED PYRROLIDINE AMIDES V NR3C1, NR3C2, MC2R GPR119 200/4885RIPK1 3497/4885RORC 297/4885
US-20080221151-A1 3-AMINO-2-PHENYLPYRROLIDINE DERIVATIVES PBK, KCND3, KCND2 GPR119 819/4885RIPK1 4328/4885RORC 3074/4885
US-12331034-B2 Substituted pyrrolidine amides V NR3C1, NR3C2, MC2R GPR119 200/4885RIPK1 3497/4885RORC 297/4885
US-20060035935-A1 Acylated piperidine derivatives as melanocortin-4 receptor agonists MC4R, MC5R, MC3R GPR119 12/4885RIPK1 3353/4885RORC 1740/4885
US-20050288358-A1 3-amino-2-phenylpyrrolidine derivatives PBK, KCND3, KCND2 GPR119 819/4885RIPK1 4328/4885RORC 3074/4885
US-20040097546-A1 Acylated piperidine derivatives as melanocortin-4 receptor agonists MC4R, MC5R, MC3R GPR119 12/4885RIPK1 3353/4885RORC 1740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.