Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 17/20 | 0.54 |
| ▸ | HRH2 | P25021 | 10/20 | 0.54 |
| ▸ | HRH1 | P35367 | 10/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18635740 | 0.83 | TMEM97 (0.64) | HRH3HRH1MAPK1RAB9ACYP2D6 | |
| SCHEMBL13376182 | 0.82 | HRH3 (0.54) | HRH3HRH2HRH1MAPK1RAB9A | |
| SCHEMBL10222499 | 0.81 | HRH3 (0.75) | HRH3HRH2HRH1 | |
| SCHEMBL21814266 | 0.80 | SIGMAR1 (0.62) | HRH3HRH2HRH1 | |
| SCHEMBL3582593 | 0.79 | HRH3 (0.64) | HRH3HRH2HRH1 | |
| SCHEMBL14618951 | 0.78 | HRH3 (0.67) | HRH3HRH2HRH1 | |
| SCHEMBL21814280 | 0.75 | HRH3 (0.73) | HRH3HRH2HRH1 | |
| SCHEMBL4473444 | 0.75 | HRH3 (0.73) | HRH3HRH2HRH1 | |
| SCHEMBL21251621 | 0.74 | TMEM97 (0.72) | HRH3HRH1MAPK1RAB9ACYP2D6 | |
| SCHEMBL20236602 | 0.74 | MAPK1 (0.68) | HRH3MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007116092-A1 | ENZYME INHIBITORS | PROBIODRUG AG (DE) | 2007-10-18 | — | — | WO | disclosed |