Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR3 | Q99500 | 5/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 11/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 10/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.31 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL22797917 | 0.78 | SLC6A4 (0.43) | SLC6A4SLC6A2SLC6A3KCNH2EPHX1 | |
| SCHEMBL296408 | 0.78 | GABRA1 (0.39) | SLC6A4SLC6A2SLC6A3KCNH2EPHX1 | |
| Hydrochloric Acid SCHEMBL3746410 | 0.76 | GABRA1 (0.38) | SLC6A4SLC6A2SLC6A3KCNH2EPHX1 | |
| SCHEMBL2606468 | 0.70 | S1PR3 (0.48) | S1PR3S1PR1EPHX1TSHR | |
| SCHEMBL15261351 | 0.69 | SPHK1 (0.45) | S1PR3S1PR1SPHK1TSHR | |
| SCHEMBL16795227 | 0.69 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNH2EPHX1 | |
| SCHEMBL19400548 | 0.69 | EPHX1 (0.39) | S1PR3S1PR1EPHX1TSHR | |
| SCHEMBL1712105 | 0.67 | SPHK1 (0.47) | S1PR3S1PR1SPHK1TSHR | |
| Hydrochloric Acid SCHEMBL28819699 | 0.67 | SPHK1 (0.44) | S1PR3S1PR1SPHK1TSHR | |
| Tert-Butyl Formate SCHEMBL28007136 | 0.67 | TDP1 (0.39) | SLC6A4SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007142583-A1 | MUSCARINIC RECEPTOR AGONISTS THAT ARE EFFECTIVE IN THE TREATMENT OF PAIN, ALZHEIMER'S DISEASE AND SCHIZOPHRENIA. | ASTRAZENECA AB (SE) | 2007-12-13 | — | — | WO | disclosed |