Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | LIPE | Q05469 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15731643 | 0.96 | EPHX1 (0.34) | EPHX1S1PR3CA1CA2CA4 | |
| SCHEMBL15731645 | 0.86 | — | — | |
| SCHEMBL283047 | 0.86 | ALDH1A1 (0.33) | GAATSHRALDH1A1 | |
| SCHEMBL283046 | 0.86 | ALDH1A1 (0.33) | GAATSHRALDH1A1 | |
| SCHEMBL284320 | 0.86 | ALDH1A1 (0.33) | GAATSHRALDH1A1 | |
| SCHEMBL8977208 | 0.81 | EPHX1 (0.38) | EPHX1S1PR3CA1CA2CA4 | |
| SCHEMBL15223835 | 0.80 | SIGMAR1 (0.32) | EPHX1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27528154 | 0.79 | EPHX1 (0.45) | EPHX1S1PR3CA1CA2CA4 | |
| SCHEMBL13191373 | 0.78 | TAS1R3 (0.37) | EPHX1S1PR3CA1CA2CA4 | |
| SCHEMBL24260119 | 0.77 | THRB (0.36) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170333567-A1 | Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers | SYNTARGA BV (NL) | 2017-11-23 | — | — | US | disclosed |
| US-20170274090-A1 | Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers | SYNTARGA BV (NL) | 2017-09-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170274090-A1 | Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers | PCNA, DCLRE1A, CDC5L | EPHX1 2864/4885S1PR3 1897/4885CA1 447/4885 |
| US-20170333567-A1 | Novel Conjugates of CC-1065 Analogs and Bifunctional Linkers | PCNA, DCLRE1A, CDC5L | EPHX1 2864/4885S1PR3 1897/4885CA1 447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.