Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | STS | P08842 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218920 | 0.88 | GPR119 (0.48) | STSGPR119NAMPT | |
| SCHEMBL3987027 | 0.81 | MEN1 (0.48) | MEN1KMT2ASTSNPSR1USP2 | |
| SCHEMBL3992245 | 0.79 | CACNA1H (0.59) | MEN1KMT2ASTSHTT | |
| SCHEMBL4412432 | 0.79 | CACNA1H (0.57) | MEN1KMT2ASTSNPSR1USP2 | |
| SCHEMBL8213940 | 0.77 | CACNA1H (0.59) | MEN1KMT2ASTSNPSR1USP2 | |
| SCHEMBL4417927 | 0.76 | GPR119 (0.48) | MEN1KMT2ASTSNPSR1USP2 | |
| SCHEMBL30901891 | 0.76 | NAMPT (0.37) | MEN1KMT2AGPR119NAMPT | |
| SCHEMBL3613790 | 0.75 | MEN1 (0.47) | MEN1KMT2ASTSNPSR1USP2 | |
| SCHEMBL8310737 | 0.75 | NAMPT (0.60) | MEN1KMT2ASTSNPSR1USP2 | |
| SCHEMBL31066539 | 0.74 | USP2 (0.45) | USP2HPGDGPR119NAMPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033456-A1 | SPIRO-CONDENSED AZETIDINE DERIVATIVES USEFUL IN TREATING PAIN, DIABETES AND DISORDERS OF LIPID METABILISM | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |