Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 3/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8224867 | 0.88 | MEN1 (0.49) | GPR119NAMPTSTS | |
| SCHEMBL8201517 | 0.80 | GPR119 (0.47) | GPR119TSHRALOX15ATMKDM4E | |
| SCHEMBL31066539 | 0.76 | USP2 (0.45) | GPR119KDM4ENAMPT | |
| SCHEMBL13277183 | 0.76 | GPR119 (0.44) | GPR119TSHRALOX15ATMKDM4E | |
| SCHEMBL8218899 | 0.76 | GPR119 (0.48) | GPR119TSHRALOX15ATMKDM4E | |
| SCHEMBL17725555 | 0.75 | GPR119 (0.50) | GPR119TSHRALOX15ATMKDM4E | |
| SCHEMBL8212694 | 0.74 | TRPV1 (0.61) | GPR119TSHRALOX15ATMRORC | |
| SCHEMBL12493066 | 0.74 | GPR119 (0.44) | GPR119TSHRALOX15ATMKDM4E | |
| SCHEMBL3843148 | 0.73 | NAMPT (0.66) | GPR119KDM4EPKMNAMPTSTS | |
| SCHEMBL4334410 | 0.73 | SLC6A9 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033460-A2 | TREATING PAIN, DIABETES, AND LIPID METABOLISM DISORDERS | SCHERING CORPORATION (US) | 2008-03-20 | — | — | WO | disclosed |