Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | ACHE | P22303 | 4/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ESRRG | P62508 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.48 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.45 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.45 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL740549 | 1.00 | KMT2A (0.67) | KMT2AACHEL3MBTL1KDM4EESRRG | |
| SCHEMBL2163478 | 0.80 | KMT2A (1.00) | KMT2AL3MBTL1KDM4EMAPTGFER | |
| SCHEMBL2229059 | 0.80 | KMT2A (1.00) | KMT2AL3MBTL1KDM4EMAPTGFER | |
| SCHEMBL2163477 | 0.80 | KMT2A (1.00) | KMT2AL3MBTL1KDM4EMAPTGFER | |
| SCHEMBL9938969 | 0.78 | KDM1A (0.60) | KMT2AACHEL3MBTL1KDM4EMAPT | |
| SCHEMBL21215365 | 0.78 | KDM1A (0.60) | KMT2AACHEL3MBTL1KDM4EMAPT | |
| SCHEMBL9938975 | 0.78 | KDM1A (0.60) | KMT2AACHEL3MBTL1KDM4EMAPT | |
| SCHEMBL4275683 | 0.78 | KMT2A (0.64) | KMT2AACHEL3MBTL1KDM4EMAPT | |
| SCHEMBL27198359 | 0.78 | KMT2A (0.64) | KMT2AACHEL3MBTL1KDM4EMAPT | |
| SCHEMBL5668373 | 0.78 | KMT2A (0.64) | KMT2AACHEL3MBTL1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007115403-A1 | COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS | PAINCEPTOR PHARMA CORPORATION (CA) | 2007-10-18 | — | — | WO | disclosed |