Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 17/20 | 0.76 |
| ▸ | SIRT2 | Q8IXJ6 | 15/20 | 0.76 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL907810 | 0.89 | SIRT1 (0.78) | SIRT1SIRT2SIRT3 | |
| SCHEMBL907692 | 0.88 | SIRT1 (0.78) | SIRT1SIRT2SIRT3 | |
| SCHEMBL907340 | 0.88 | SIRT1 (0.78) | SIRT1SIRT2SIRT3 | |
| SCHEMBL907437 | 0.87 | SIRT1 (0.76) | SIRT1SIRT2SIRT3 | |
| SCHEMBL907478 | 0.86 | SIRT1 (1.00) | SIRT1SIRT2SIRT3 | |
| SCHEMBL907464 | 0.85 | SIRT1 (1.00) | SIRT1SIRT2SIRT3 | |
| Hydrochloric Acid SCHEMBL907346 | 0.85 | SIRT1 (1.00) | SIRT1SIRT2SIRT3 | |
| SCHEMBL907754 | 0.85 | SIRT1 (1.00) | SIRT1SIRT2SIRT3 | |
| SCHEMBL907349 | 0.85 | SIRT1 (1.00) | SIRT1SIRT2SIRT3 | |
| Hydrochloric Acid SCHEMBL907338 | 0.84 | SIRT1 (0.71) | SIRT1SIRT2SIRT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099445-B1 | P53 ACTIVATING BENZOYL UREA AND BENZOYL THIOUREA COMPOUNDS | UNIV DUNDEE (GB) | 2010-11-17 | — | — | EP | disclosed |
| WO-2008029096-A2 | P53 ACTIVATING BENZOYL UREA AND BENZOYL THIOUREA COMPOUNDS | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2008-03-13 | — | — | WO | disclosed |