Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA7 | P43166 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.62 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7129676 | 0.89 | HPGD (0.79) | HPGDALDH1A1USP2CA12CA1 | |
| SCHEMBL252026 | 0.89 | HPGD (0.79) | HPGDALDH1A1USP2CA12CA1 | |
| Hydrochloric Acid SCHEMBL1597472 | 0.87 | HPGD (0.76) | HPGDALDH1A1USP2CA12CA1 | |
| SCHEMBL1938606 | 0.83 | HPGD (0.70) | HPGDALDH1A1USP2CA12CA1 | |
| SCHEMBL27989163 | 0.83 | ALDH1A1 (0.85) | HPGDALDH1A1USP2CA12CA1 | |
| SCHEMBL2614241 | 0.83 | HPGD (0.84) | HPGDALDH1A1USP2CA12CA1 | |
| SCHEMBL4143492 | 0.82 | HPGD (0.68) | HPGDALDH1A1USP2CA12CA1 | |
| SCHEMBL1263133 | 0.81 | HPGD (0.88) | HPGDALDH1A1USP2SIGMAR1BLM | |
| SCHEMBL254870 | 0.81 | HPGD (0.96) | HPGDALDH1A1USP2SIGMAR1BLM | |
| SCHEMBL18228404 | 0.81 | HPGD (0.96) | HPGDALDH1A1USP2SIGMAR1BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104193750-B | Suppress mitotic Compounds and methods for by suppressing aurora kinase | 千禧药品公司 | 2018-04-27 | — | — | CN | disclosed |
| WO-2013096744-A1 | HEPATITIS B ANTIVIRAL AGENTS | NOVIRA THERAPEUTICS, INC. (US) | 2013-06-27 | — | — | WO | disclosed |
| WO-2007144639-A1 | 2 -OXYBENZAMIDE DERIVATIVES AS PARP INHIBITORS | KUDOS PHARMACEUTICALS LIMITED (GB) | 2007-12-21 | — | — | WO | disclosed |
| EP-0436734-B1 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO (JP) | 1995-10-11 | — | — | EP | disclosed |
| EP-0436734-A1 | NEW AMINOPIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-07-17 | — | — | EP | disclosed |
| EP-0215902-A1 | PROCESS FOR 4-AMINO QUINOLINES | THE UPJOHN COMPANY (US) | 1987-04-01 | — | — | EP | disclosed |
| WO-1986005489-A1 | PROCESS FOR 4-AMINO QUINOLINES | THE UPJOHN COMPANY (US) | 1986-09-25 | — | — | WO | disclosed |
| US-4167567-A | Antihypertensive 4-aminoquinolines | THE UPJOHN COMPANY (US) | 1979-09-11 | — | — | US | disclosed |