Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.40 |
| ▸ | CPA1 | P15085 | 2/20 | 0.38 |
| ▸ | CPB1 | P15086 | 1/20 | 0.38 |
| ▸ | CPA3 | P15088 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9116270 | 0.87 | ALDH1A1 (0.42) | GABBR2GABBR1CYP2C19MAPTLMNA | |
| SCHEMBL9116274 | 0.87 | ALDH1A1 (0.42) | GABBR2GABBR1CYP2C19MAPTLMNA | |
| SCHEMBL28442232 | 0.86 | FFAR1 (0.42) | CYP2C19MAPTFFAR1LMNACYP2D6 | |
| SCHEMBL3667777 | 0.86 | FFAR1 (0.42) | CYP2C19MAPTFFAR1LMNACYP2D6 | |
| SCHEMBL3664365 | 0.86 | FFAR1 (0.42) | CYP2C19MAPTFFAR1LMNACYP2D6 | |
| SCHEMBL3664366 | 0.86 | FFAR1 (0.42) | CYP2C19MAPTFFAR1LMNACYP2D6 | |
| SCHEMBL3667776 | 0.86 | FFAR1 (0.42) | CYP2C19MAPTFFAR1LMNACYP2D6 | |
| SCHEMBL2501300 | 0.84 | KYNU (0.42) | GABBR2GABBR1LMNAMEN1KMT2A | |
| SCHEMBL2501109 | 0.84 | KYNU (0.42) | GABBR2GABBR1LMNAMEN1KMT2A | |
| SCHEMBL3719120 | 0.81 | FFAR1 (0.60) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007133865-A2 | HCV/HIV INHIBITORS AN THEIR USES | NOVARTIS AG (CH) | 2007-11-22 | — | — | WO | disclosed |