Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.44 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.44 |
| ▸ | PHGDH | O43175 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Xylene SCHEMBL10608254 | 0.93 | MAPT (0.49) | ALDH1A1MAPTKMT2ACYP11B1CYP11B2 | |
| SCHEMBL17279861 | 0.92 | KMT2A (0.47) | ALDH1A1MAPTKMT2ACYP11B1CYP11B2 | |
| SCHEMBL22307603 | 0.92 | ALDH1A1 (0.46) | ALDH1A1MAPTKMT2ACYP11B1CYP11B2 | |
| SCHEMBL14081503 | 0.91 | ESRRA (0.52) | ALDH1A1MAPTKMT2ACYP11B1CYP11B2 | |
| SCHEMBL14081499 | 0.91 | ESRRA (0.52) | ALDH1A1MAPTKMT2ACYP11B1CYP11B2 | |
| SCHEMBL17279807 | 0.89 | ESRRA (0.58) | ALDH1A1MAPTKMT2ACYP11B1POLB | |
| SCHEMBL17372934 | 0.89 | MAPT (0.53) | ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL14458205 | 0.84 | MAPT (0.46) | ALDH1A1MAPTKMT2APOLB | |
| SCHEMBL13098206 | 0.83 | FYN (0.48) | ALDH1A1MAPTKMT2ACYP11B1CYP11B2 | |
| SCHEMBL11711938 | 0.82 | SMN1; SMN2 (0.47) | ALDH1A1MAPTKMT2APOLBSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106164060-A | Oxirane compound and method for producing nitrogen-containing heterocyclic compound using same | 日本电石工业株式会社 | 2016-11-23 | — | — | CN | claimed |
| CN-110483400-B | Preparation method of pyrazole derivative | 上海应用技术大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-114075138-A | Stable isotope labeled difenzoquat and synthetic method thereof | 上海安谱实验科技股份有限公司 | 2022-02-22 | — | — | CN | disclosed |
| CN-110483400-A | A kind of preparation method of pyrazole derivatives | SHANGHAI INST TECH | 2019-11-22 | — | — | CN | disclosed |
| CN-106164060-A | Oxirane compound and method for producing nitrogen-containing heterocyclic compound using same | 日本电石工业株式会社 | 2016-11-23 | — | — | CN | disclosed |
| US-20160178816-A1 | NEAR-INFRARED-ABSORBING COMPOSITION, NEAR-INFRARED CUT FILTER OBTAINED USING SAME, PROCESS FOR PRODUCING SAID CUT FILTER, CAMERA MODULE AND PROCESS FOR PRODUCING SAME, AND SOLID PHOTOGRAPHING ELEMENT | FUJIFILM CORPORATION (JP) | 2016-06-23 | — | — | US | disclosed |
| US-9067919-B2 | Use of dibenzofurans and dibenzothiophenes substituted by nitrogen-bonded five-membered heterocyclic rings in organic electronics | BASF SE (DE) | 2015-06-30 | — | — | US | disclosed |
| US-8735398-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-05-27 | — | — | US | disclosed |
| US-20130085147-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-04-04 | — | — | US | disclosed |
| US-8362020-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-01-29 | — | — | US | disclosed |
| CN-85108315-A | A kind of improved \" difenzoquat \" synthesis method | — | 1987-05-13 | — | — | CN | disclosed |
| EP-0155492-A1 | Preparation of 1-alkyl-3,5-diphenylpyrazoles | AMERICAN CYANAMID COMPANY (US) | 1985-09-25 | — | — | EP | disclosed |
| US-4482745-A | ACETOPHENONE, METHYL BENZOATE, CALCIUM OXIDE | AMERICAN CYANAMID COMPANY (US) | 1984-11-13 | — | — | US | disclosed |
| EP-0023422-B1 | HERBICIDAL SULFONAMIDES, PREPARATION AND USE THEREOF, AND COMPOSITIONS CONTAINING THEM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-02-22 | — | — | EP | disclosed |
| WO-1981000665-A1 | PLANT PHYSIOLOGICALLY ACTIVE COMPOSITION AND USE | FISONS LTD (GB) | 1981-03-19 | — | — | WO | disclosed |
| US-4170464-A | SYNERGISTIC 1,2-DIALKYL-3,5-DIPHENYL PYRAZOLIUM SALT AND A PHENOXYACETIC ACID | AMERICAN CYANAMID COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| US-4162913-A | HERBICIDE, CONTROLLING WILD OATS | AMERICAN CYANAMID CO. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4014896-A | Catalytic dehydrogenation process for the preparation of 3,4,5-trisubstituted pyrazoles | AMERICAN CYANAMID COMPANY (US) | 1977-03-29 | — | — | US | disclosed |
| US-3979409-A | DEHYDROGENATION WITH N-BROMO OR N-CHLORO-SUCCINIMIDE | AMERICAN CYANAMID COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
| US-3952010-A | MULTISTAGE, FROM A KETONE AND AN ALDEHYDE, HYDRAZINE | AMERICAN CYANAMID COMPANY (US) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130085147-A1 | Hepatitis C Virus Inhibitors | HAVCR2, MAVS, GTF3C1 | ALDH1A1 3778/4885MAPT 2725/4885KMT2A 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.